Bioinspired Choline-like Ionic Liquids: Their Penetration Ability through Cell Membranes and Application to SEM Visualization of Hydrous Samples

Kawai, Koji; Kaneko, Kotaro; Kawakami, Hayato; Yonezawa, Tetsu

doi:10.1021/la201914h

Cited by 42 publications

(34 citation statements)

References 23 publications

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“…In addition to this, we found that a thin RTIL layer spread on insulating materials works as a conductive layer like a thin Au layer when such materials are observed by using a common SEM system [10]–[13]. Since our first report [9], a number of similar works have been reported by various research groups [14]–[20].…”

Section: Introductionsupporting

confidence: 69%

SEM Observation of Hydrous Superabsorbent Polymer Pretreated with Room-Temperature Ionic Liquids

et al. 2014

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Room-temperature ionic liquid (RTIL), which is a liquid salt at or below room temperature, shows peculiar physicochemical properties such as negligible vapor pressure and relatively-high ionic conductivity. In this investigation, we used six types of RTILs as a liquid material in the pretreatment process for scanning electron microscope (SEM) observation of hydrous superabsorbent polymer (SAP) particles. Very clear SEM images of the hydrous SAP particles were obtained if the neat RTILs were used for the pretreatment process. Of them, tri-n-butylmethylphosphonium dimethylphosphate ([P4, 4, 4, 1][DMP]) provided the best result. On the other hand, the surface morphology of the hydrous SAP particles pretreated with 1-ethyl-3-methylimidazolium tetrafluoroborate ([C2mim][BF4]) and 1-butyl-3-methylimidazolium tetrafluoroborate ([C4mim][BF4]) was damaged. The results of SEM observation and thermogravimetry analysis of the hydrous SAP pretreated with the RTILs strongly suggested that most water in the SAP particles are replaced with RTIL during the pretreatment process.

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Section: Introductionsupporting

confidence: 69%

SEM Observation of Hydrous Superabsorbent Polymer Pretreated with Room-Temperature Ionic Liquids

et al. 2014

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“…It has been known recently that IL possess ionic conductivity and lack electric conductivity which makes them quite suitable for SEM observation giving contrast images without noise, and keeps the sample in wet condition shown in Fig. 8, Panel B and C [61,62]. At CMC (100 mM) the size of the vesicles increases largely and the BMOP forms a film around the gramicidin vesicle, this type of behaviour of the pyrrolidinium based IL with vesicles has been reported earlier [23].…”

Section: Fesem Characterizationsupporting

confidence: 63%

Effect of pyrrolidinium based ionic liquid on the channel form of gramicidin in lipid vesicles

Singh

Dohare

Mishra

et al. 2015

Journal of Photochemistry and Photobiology B: Biology

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“…In a highly innovative application, Kawai et al 314 prepared several choline-like hydrophilic ILs (hydroxyl- and/or carboxyl-functionalized ammonium ILs with CH 3 SO 3 − as the anion), and showed their potential for visualizing samples by scanning electron microscopy (SEM), including hydrated samples such as seaweed and foodstuffs. It was found that this sample treatment prior to SEM analysis allows for the visualization of samples without charging and without metal sputtering.…”

Section: Applications Of Ether- and Hydroxyl-functionalized Ilsmentioning

confidence: 99%

Ether- and alcohol-functionalized task-specific ionic liquids: attractive properties and applications

2012

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In recent years, the designer nature of ionic liquids (ILs) has driven their exploration and exploitation in countless fields among the physical and chemical sciences. A fair measure of the tremendous attention placed on these fluids has been attributed to their inherent designer nature. And yet, there are relatively few examples of reviews which emphasize this vital aspect in an exhaustive or meaningful way. In this critical review, we systematically survey the physicochemical properties of the collective library of ether- and alcohol-functionalized ILs, highlighting the impact of ionic structure on features such as viscosity, phase behavior/transitions, density, thermostability, electrochemical properties, and polarity (e.g., hydrophilicity, hydrogen bonding capability). In the latter portions of this review, we emphasize the attractive applications of these functionalized ILs across a range of disciplines, including their use as electrolytes or functional fluids for electrochemistry, extractions, biphasic systems, gas separations, carbon capture, carbohydrate dissolution (particularly, the (ligno)celluloses), polymer chemistry, antimicrobial and antielectrostatic agents, organic synthesis, biomolecular stabilization and activation, and nanoscience. Finally, this review discusses anion-functionalized ILs, including sulfur- and oxygen-functionalized analogs, as well as choline-based deep eutectic solvents (DESs), an emerging class of fluids which can be sensibly categorized as semi-molecular cousins to the IL. Finally, the toxicity and biodegradability of ether- and alcohol-functionalized ILs are discussed and cautiously evaluated in light of recent reports. By carefully summarizing literature examples on the properties and applications of oxy-functional designer ILs up till now, it is our intent that this review offer a barometer for gauging future advances in the field as well as a trigger to spur further contemplation of these seemingly inexhaustible and—relative to their potential—virtually untouched fluids. It is abundantly clear that these remarkable fluidic materials are here to stay, just as certain design rules are slowly beginning to emerge. However, in fairness, serendipity also still plays an undeniable role, highlighting the need for both expanded in silico studies and a beacon to attract bright, young researchers to the field.

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Bioinspired Choline-like Ionic Liquids: Their Penetration Ability through Cell Membranes and Application to SEM Visualization of Hydrous Samples

Cited by 42 publications

References 23 publications

SEM Observation of Hydrous Superabsorbent Polymer Pretreated with Room-Temperature Ionic Liquids

SEM Observation of Hydrous Superabsorbent Polymer Pretreated with Room-Temperature Ionic Liquids

Effect of pyrrolidinium based ionic liquid on the channel form of gramicidin in lipid vesicles

Ether- and alcohol-functionalized task-specific ionic liquids: attractive properties and applications

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