“…The studies on the transient assembly of macroscopic gels mediated by CRNs, 28 transient healing ability of kinetically inert gels, 29,44,90,91 and self-reporting via cascade reaction-regulated CL 45,106 are pioneered by our research group, and these contributions have made significant impacts on the fields of damage-reporting and self-healing materials, macroscopic supramolecular assembly, and metastable materials. 1,5,[112][113][114][115][116] Moreover, the CRNs present an opportunity to construct a range of complex functional gels with various excellent features from a single responsive material, expanding the scope of applications of gels. Despite the systematicity and relative maturity of the reported transiently regulated gels designed and developed based on CRNs, many challenges remain and promising applications are yet to be explored (Fig.…”