Bioisosterically modified dipeptide excitatory amino acid receptor antagonists containing 3-oxygenated isothiazole ring systems

Matzen, Lisa; Ebert, Bjarke; Stensbøl, Tine B.; Frølund, Bente; Jaroszewski, Jerzy W.; Krogsgaard‐Larsen, Povl

doi:10.1016/s0968-0896(97)00110-7

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Areas Of Application Of Isothiazoles1

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2002

2021

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Cited by 5 publications

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“…289 ± 291 2-Amino-3-(3-hydroxy-5-methylisothiazol-4-yl)propionic acid (280), the isothiazole analogue of 2-amino-3-(3hydroxy-5-methylisoxazol-4-yl)propionic acid (281, AMPA), blocks the activation of glutamate receptors which are crucial for brain ischemia, Alzheimer's disease, hypoglycemia, etc. 292,293…”

Section: Areas Of Application Of Isothiazolesmentioning

confidence: 99%

Isothiazoles (1,2-thiazoles): synthesis, properties and applications

Kaberdin¹,

Поткин²

2002

Russ. Chem. Rev.

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The most recent achievements in the chemistry of The most recent achievements in the chemistry of isothiazoles are generalised and systematised. The main applica-isothiazoles are generalised and systematised. The main applications of isothiazole derivatives are surveyed. The bibliography tions of isothiazole derivatives are surveyed. The bibliography includes 293 references includes 293 references. .

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Section: Areas Of Application Of Isothiazolesmentioning

confidence: 99%