Biological activities of the extracts of two endemic Sideritis species in Turkey

Sağdıç, Osman; Aksoy, Ahmet; Ozkan, Gülcan; Ekici, Lütfiye; Albayrak, Sevil

doi:10.1016/j.ifset.2007.06.001

Cited by 35 publications

(28 citation statements)

References 25 publications

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“…A study Previous studies reported a high correlation between the antioxidant capacity and phenolic constituents of methanol extracts from medicinal plants (Miceli et al, 2005;Maisuthisakul et al, 2007;Li et al, 2008;Sagdic et al, 2008). The present results show that N. italica and S. montana exhibit antioxidant properties.…”

Section: Flavonoid Contentssupporting

confidence: 66%

“…The methanol extracts of N. italica and S. montana almost completely inhibited (Table 4). A previous study reported that the Sideritis species could be used as natural antimicrobial and antioxidant agents in food preservation and human health (Sagdic et al, 2008). Several studies suggested that Nepeta and Sideritis species have antimicrobial and antifungal activities (Diaz et al, 1988;Ezer and Abbasog lu, 1996;Nostro et al, 2001;Basile et al, 2006).…”

Section: Radical Scavenging Activity By Dpph Methodsmentioning

confidence: 99%

“…Sideritis is represented by 45 species and 53 taxa, of which 39 species are endemic in Turkey (Davis, 1982;Nakibog lu et al, 2007). The endemism ratio of the Sideritis species is very high (78%) for Turkey among other Lamiaceae species (Sagdic et al, 2008). Sideritis species are used in folk medicine as anti-inflammatory, anti-ulcer, cytostatic, antimicrobial, flu vaccine and stimulant circulatory agents (Basile et al, 2006).…”

Section: Chromatographic Analysis and Quantification Of Lipid Solublementioning

confidence: 99%

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Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. montana from Turkey

et al. 2011

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RESUMENCompuestos biológicos, capacidad atrapadora de radicales libres y actividad antimicrobiana de las semillas de Nepeta italica L. y Sideritis montana L. subsp. montana de Turquía.Este estudio ha determinado algunos compuestos bioló-gicos (ácidos grasos, vitaminas liposolubles, esteroles y flavonoides), capacidad atrapadora de radicales libres, y actividades antimicrobianas de las semillas de Nepeta italica L. y Sideritis montana L. subsp. montana. Se encontró que el áci-do palmítico (C16:0; 8.54±0.13-3.05±0.04%), ácido oleico (C18:1 n9, 22.41±0.8-18.83±0.1%) y α-linolénico (C18:3 n 3;39.56±0.67-77.04±2.07%) eran mayoritarios en ambas semillas de Nepeta italica L. y Sideritis montana L. subsp. montana. Además, se determinó que tanto Nepeta italica L. como Sideritis montana L. subsp. montana contenían estigmasterol (630.07±1.81μg/g; 80,74±0.71μg/g, respectivamente) y ergosterol (11.01±0.14 μg/g; 161.32±0.63 μg/g respectivamente) y esta última además beta-sitosterol (2.93±0.03μg/g). Además, los resultados muestran que Nepeta italica L. contiene morin (37.79±1.09μg/g), catequina (124.39±2.23μg/g) y naringina (475.96±3.57μg/g) y Sideritis montana L. subsp. montana contiene morin (188.41±2.53μg/g), catequina (64.14±1.86μg/g), naringenina (38.34±1.78 μg/g), como principales flavonoides. También, se determinó que los extractos metanólicos de Nepeta itálica L. y Sideritis montana L. subsp. montana fueron eficaces contra los radicales DPPH. Los resultados obtenidos en el presente estudio mostraron que las vitaminas, los flavonoides y los ácidos grasos de los extractos en las semillas de Nepeta itálica L. y Sideritis montana L. subsp. montana impidieron el crecimiento de los microorganismos utilizados en el ensayo, en diferentes proporciones. PALABRAS CLAVE: Ácidos grasos -Actividad antimicrobiana -DPPH radical scavenging actividad -Esteroles

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Section: Flavonoid Contentssupporting

confidence: 66%

Section: Radical Scavenging Activity By Dpph Methodsmentioning

confidence: 99%

Section: Chromatographic Analysis and Quantification Of Lipid Solublementioning

confidence: 99%

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Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. montana from Turkey

et al. 2011

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“…is called çay çalbası [4] and eldiven çayı [5] by local people. Up to now, several biological activities such as antioxidant, anticonvulsant, antispasmodic, anti-inflammatory, anti-rheumatic, antiulcer, antimicrobial, cytotoxic, and analgesic have been reported from Sideritis species [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

Deveci¹,

Tel‐Çayan²,

Yıldırım³

et al. 2017

mpj

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The objective of this study was to investigate the chemical composition, antioxidant, anticholinesterase and anti-urease activities of essential oil, hexane, acetone and methanol extracts of Sideritis pisidica Boiss. & Heldr. The essential oil and fatty acid composition were analyzed by GC and GC/MS. δ-Cadinene (19.5 %), T-cadinol (16.7 %) and β-cubebene (10.4 %) were identified as the main compounds of the essential oil whereas the most abundant compounds of fatty acids were found as linolenic (42.7 %), palmitic (31.3 %) and linoleic (13.4%) acids. The methanol extract demonstrated the highest antioxidant activity in all tests, except for metal chelating assay. The hexane extract was found to be significantly active in metal chelating (IC 50 : 22.97±1.36 µg/mL), acetylcholinesterase (62.54±0.88 %) and urease inhibitory (78.93±0.17 %) assays. These results show that the Sideritis pisidica could be used as the potential source of natural products in the food and pharmaceutical areas.

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“…In vitro and epidemiological studies strongly suggest that consumption of a variety of phenolic compounds could significantly lower the risk of serious health disorders for the antibacterial, antimutagenic and anti-inflammatory activity of phenolics (Albayrak, Aksoy, Sagdic, & Hamzaoglu, 2010;Lou, Wang, Li et al, 2010;Senevirathne et al, 2006;Surh, 2002;Surh et al, 1999;Tu, Sun, Tian, Xie, & Chen, 2009), therefore, more and more attention is being paid on phenolic compounds (Liu, Qiu, Ding, & Yao, 2008;Ozkan, Sagdic, Gokturk, Unal, & Albayrak, 2010;Sagdic, Aksoy, Ozkan, Ekici, & Albayrak, 2008).…”

Section: Introductionmentioning

confidence: 99%

p-Coumaric acid kills bacteria through dual damage mechanisms

et al. 2012

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Biological activities of the extracts of two endemic Sideritis species in Turkey

Cited by 35 publications

References 25 publications

Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of <i>Nepeta italica</i> L. and <i>Sideritis montana</i> L. subsp. <i>montana</i> from Turkey

Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of <i>Nepeta italica</i> L. and <i>Sideritis montana</i> L. subsp. <i>montana</i> from Turkey

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

p-Coumaric acid kills bacteria through dual damage mechanisms

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