Biomass-Derived Dialdehyde Cellulose Cross-linked Chitosan-Based Nanocomposite Hydrogel with Phytosynthesized Zinc Oxide Nanoparticles for Enhanced Curcumin Delivery and Bioactivity

George, Dhanya; Maheswari, Palanisamy Uma; Begum, K.M. Meera Sheriffa; Arthanareeswaran, G.

doi:10.1021/acs.jafc.9b01933

Cited by 76 publications

(34 citation statements)

References 57 publications

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“…Their porous structure and swelling property in aqueous media make them suitable for drug loading and delivery. George et al [101] have observed the incorporation of ZnO NPs in dimethyl cellulose crosslinked chitosan hydrogel promoted the drug loading capacity of the gel. They obtained a 30% increment in loading efficiency by incorporating ZnO nanoparticles.…”

Section: Curcumin-metal Oxides Incorporated Hydrogelsmentioning

confidence: 99%

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

et al. 2021

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In the past few decades, curcumin, a natural polyphenolic phytochemical, has been studied for treating a wide variety of diseases. It has shown promising results as a potential curative agent for a variety of diseases. However, its inherent limitations, such as poor aqueous solubility, poor absorbability, fast metabolic rate, and quick elimination from the body, have limited its application beyond preclinical studies. A huge number of studies have been made to address the issues of curcumin and to maximally utilize its potentials. Many review articles have tried to assess and summarize different nanocarriers, especially organic nanocarriers, for nanoformulations with curcumin. Nevertheless, few exclusive reviews on the progress in nanoformulation of curcumin with inorganic nanomaterials have been made. In this review, we present an exclusive summary of the progress in nanoformulation of curcumin with metal oxide nanoparticles. The beneficial feature of the metal oxide nanoparticles used in the curcumin nanoformulation, the different approaches followed in formulating curcumin with the metal oxides, and the corresponding results, protective effect of curcumin from different metal oxide caused toxicities, and concluding remarks are presented in the review.

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Section: Curcumin-metal Oxides Incorporated Hydrogelsmentioning

confidence: 99%

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

et al. 2021

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“…This hydrogel exhibits antimicrobial activity towards Staphylococcus aureus and Trichophyton rubrum. [13] Furthermore, they loaded the curcumin into the hydrogel and studied the diffusion-controlled release mechanism of the loaded drug. Abhishek Gupta et al synthesized the silver nanoparticle by using curcumin-cyclodextrin and incorporated these nanoparticles into the bacterial cellulose (BC) hydrogel.…”

Section: Cellulose-based Antimicrobial Hydrogelmentioning

confidence: 99%

“…The ZnO NPs increase the swelling degree of the hydrogel. This hydrogel exhibits antimicrobial activity towards Staphylococcus aureus and Trichophyton rubrum [13] . Furthermore, they loaded the curcumin into the hydrogel and studied the diffusion‐controlled release mechanism of the loaded drug.…”

Section: Biopolymer‐based Hydrogelsmentioning

confidence: 99%

Antimicrobial Hydrogels: Promising Soft Biomaterials

Kundu

Payal

2020

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Hydrogel is a three‐dimensional, hydrophilic network of cross‐linked monomer or polymer units. A modified version of the hydrogel which exhibits antimicrobial properties is known as antimicrobial hydrogel. Antimicrobial properties of the antimicrobial hydrogel are due to the inheritance of antimicrobial monomers/polymers or due to the installation by the incorporation of antimicrobial agents such as a metal nanoparticle, metal oxide, antibiotics, and any other synthetic drug molecule. More attention has been taken towards antimicrobial hydrogel as the pharmaceutical and biomedical field facing the problem of drug resistance. Antimicrobial hydrogel provides a suitable alternative for antibiotic drugs and also successful to replace many antibiotic drugs which cause a serious side effect on the human body. Antimicrobial hydrogel targets the cell membrane of the microorganism and destroys them. Due to this unique type of cell lysis mechanism, microbes are rarely able to develop resistance towards antimicrobial hydrogel. The hydrogel is porous, highly flexible, and holds a particular amount of water. These properties impart a moist and living body tissue‐like environment and hence make it a suitable biomaterial to use in biomedical applications. The present article focused on the recent development of bio‐based antimicrobial hydrogels and their applications in drug delivery, wound healing and dressing, tissue engineering, and agriculture.

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“…George [265] 2019 Chitosan, Cellulose, ZnO Curcumin 65 FD Monolith Nachverarbeitung Dinu [256] 2016 Chitosan, KlinoptilolithD iclofenac-Natrium, Indomethacin > 70 FD Monolith Nachverarbeitung…”

Section: Indomethacin -F Dp Erlen Nachgelierungunclassified

Chemie der Chitosan‐Aerogele: Lenkung der dreidimensionalen Poren für maßgeschneiderte Anwendungen

et al. 2020

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Indiesem Aufsatz diskutieren wir die schnell wachsende Zahl an Literaturbeiträgen zu Chitosan-basierten porçsen Materialien, mit Schwerpunkt auf Gelierungsmechanismen, dreidimensionaler multiskaliger Strukturkontrolle sowie der mannigfaltigen chemischen Funktionalität, die mit anderen Biopolymeren nicht erreichbar ist. Die Eigenschaften unterscheiden sich von letzteren teils stark:v on überkritischg etrockneten, mesoporçsen Chitosan-Aerogelen bis hin zu äußerst leichten, gefriergetrockneten makroporçsen Gerüsten. Im Labormaßstab erreicht porçses Chitosan beeindruckende Eigenschaften, der hoch(meso)porçse Charakter verstärkt jedoch nicht nur die vorteilhafte Funktionalitätdes Chitosans,sondern auchseine Nachteile,was eine mçgliche Industrialisierung ernsthaft einschränkt. Zur Fçrderung des Technologietransfers diskutieren wir in kritischer Weise die praktische Umsetzbarkeit mçglicher Anwendungen von Chitosan-Aerogelen im Vergleich zu konventionellen und anderen biopolymerbasierten porçsen oder nichtporçsen Materialien. Aus dem Inhalt 1. Einleitung 9914 2. Synthese von Chitosan-Aerogelen 9916 3. Prozess-Struktur-Eigenschafts-Beziehungen 9920 4. Oberflächenchemie und Funktionalisierung 9925 5. Anwendungen 9927 6. Zusammenfassung und Ausblick: auf dem Wegz ur Industrialisierung 9932

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Biomass-Derived Dialdehyde Cellulose Cross-linked Chitosan-Based Nanocomposite Hydrogel with Phytosynthesized Zinc Oxide Nanoparticles for Enhanced Curcumin Delivery and Bioactivity

Cited by 76 publications

References 57 publications

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

Curcumin Nanoformulations with Metal Oxide Nanomaterials for Biomedical Applications

Antimicrobial Hydrogels: Promising Soft Biomaterials

Chemie der Chitosan‐Aerogele: Lenkung der dreidimensionalen Poren für maßgeschneiderte Anwendungen

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