Biomaterials in periodontal osseous defects

Lal, Nand; Dixit, Jaya

doi:10.1016/s2212-4268(12)60009-8

Cited by 9 publications

(7 citation statements)

References 16 publications

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“…Studies conducted by Pawar et al .,[ 17 ] Guo et al .,[ 18 ] Lal et al . [ 19 ] and Kara et al . [ 20 ] suggested that few herbs such as Drynaria quercifolia, Cissus quadrangularis, Salvia miltiorrhiza, Nigella sativa , and M. citrifolia have the ability to promote wound healing and bone repair.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment

Sabu¹,

Chandrashekar²,

Mishra³

et al. 2021

J Indian Soc Periodontol

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Background: Nature and its products can be utilized for regeneration in periodontal destruction and damage to supporting tissues. We come across the use of various graft materials to reestablish the lost bone and for the long-term survival of teeth. The objective of this study was to evaluate the bone fill efficacy of Morinda citrifolia fruit extract in the periodontal bone defect. Materials and Methods: This randomized study included twenty patients indicated for periodontal regenerative therapy and were equally divided and assigned into the experimental and control group. Open flap debridement alone was performed in the control group, while placement of extract along with open flap debridement was done in the experimental group. Clinical parameters assessed were gingival index, probing pocket depth, and relative attachment level, and the amount of bone fill was assessed using cone-beam computed tomography (CBCT) at baseline and at 6-month interval. Results: From the values of clinical parameters, there was a mean reduction in probing pocket and gain in attachment level and a 27.7% increase in bone fill in experimental group as compared to the control group from CBCT analysis. Conclusions: The use of M. citrifolia fruit extract in the intraosseous defect was found to be efficacious in terms of relative attachment level and the amount of bone fill, and it had shown some anti-inflammatory affect.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment

Sabu¹,

Chandrashekar²,

Mishra³

et al. 2021

J Indian Soc Periodontol

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“…For periodontal bone defects ( Table 6 ), 20 studies involving RCTs [ 10 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 ] and prospective CCTs [ 9 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 ] reported a parallel [ 79 , 84 , 87 ] or split mouth [ 10 , 81 , 83 , 86 ] design. The study population consisted of 12–263 persons (age, 14–75 years) divided into two to four study groups with a follow-up of 1–24 months after grafting.…”

Section: Resultsmentioning

confidence: 99%

“…The study population consisted of 12–263 persons (age, 14–75 years) divided into two to four study groups with a follow-up of 1–24 months after grafting. The outcome measures were analyzed radiographically by Intraoral Periapical (IOPA) [ 10 , 78 ], CT [86] , long cone-paralleling technique [ 80 , 85 , 91 , 94 ], computer assisted densitometry image analysis (CADIA) [87] , and other radiographic methods [ 9 , 79 , 81 , 82 , 83 , 88 , 89 , 92 , 93 ].…”

Section: Resultsmentioning

confidence: 99%

“…The control groups underwent open flap debridement (OFD) [ 9 , 10 , 78 , 79 , 80 , 81 , 82 , 86 , 88 , 89 ], demineralized freeze-dried bone allografts (DFDBA) [ 87 , 91 ], bovine bone [83] , barrier membrane (Goretex) [90] , enamel matrix derivative (EMD) [ 77 , 84 ], nonabsorbable polytetrafluoroethylene membrane (e-PTFE) [85] , and debridement only (DEBR) [93] . The test groups were alloplastic graft alone with β-tricalcium phosphate (β-TCP/HA) [77] and bonelike containing glass-reinforced HA [86] , synthetic HA alone [93] , porous HA (PHA) [90] , resorbable HA (Osteogen) [66] , or synthetic HA combined with OFD [ 9 , 78 , 88 , 89 ], PRP [78] , β-TCP [ 80 , 81 , 82 ], barrier membrane such as EMD [ 81 , 84 ], collagen membrane [79] , Goretex [90] , e-PTFE membrane [94] , bioactive glass [10] , or DFDBA [92] . The mean values and 95% CIs for the test and control groups of the selected comparable studies performed for treatment of periodontal bone defect measured in certain follow-up periods ( Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, bone surgery is performed to regenerate the lost bone and restore the alveolar ridge contour. Several grafting materials are used during surgery [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

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The use of hydroxyapatite bone substitute grafting for alveolar ridge preservation, sinus augmentation, and periodontal bone defect: A systematic review

Dewi

Ana

2018

Heliyon

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ObjectivesWe determined and structurally analyzed the reported effect of hydroxyapatite (HA) bone substitute on alveolar bone regeneration. To the best of our knowledge, no systematic reviews have previously reported the bone regenerative effect of the HA bone substitute.Materials and methodsA literature search was performed for articles published up to August 2015 using MEDLINE with the search terms “hydroxyapatite,” “bone regeneration,” and “alveolar bone” as well as their known synonyms. The inclusion criteria were set up for human trials with at least five patients. The literature search, eligible article selection, and data extraction were independently performed by two readers, and their agreement was reported by κ value.ResultsOf the 504 studies found using the MEDLINE literature search, 241 were included for further steps (inter-reader agreement, κ = 0.968). Abstract screening yielded 74 studies (κ = 0.910), with 42 completely fulfilling the inclusion criteria (κ = 0.864). In a final step, 42 studies were further analyzed, with 17 and 25 studies with and without statistical analysis, respectively. The 17 studies reporting similar outcome measures were compared using the calculated 95% confidence intervals. The effect of HA on ridge preservation could not be evaluated.ConclusionsThe use of the HA bone substitute interfered with the normal healing process, with significant differences found for sinus augmentation but not for periodontal bone defects. Thus, a bone substitute with optimal bone regenerative properties for alveolar ridge or socket preservation, sinus augmentation, and periodontal bony defect should be developed.

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Single stage reconstruction of segmental skeletal defects by bone graft in a synthetic membrane

Abdelkhalek

El-Alfy

Ali

2021

International Orthopaedics (SICOT)

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Biomaterials in periodontal osseous defects

Cited by 9 publications

References 16 publications

Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment

Evaluation of Morinda citrifolia (noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects: Clinical and cone-beam computed tomography assessment

The use of hydroxyapatite bone substitute grafting for alveolar ridge preservation, sinus augmentation, and periodontal bone defect: A systematic review

Single stage reconstruction of segmental skeletal defects by bone graft in a synthetic membrane

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