Biomaterials in rhinoplasty

Vuyk, H. D.; Adamson, Peter A.

doi:10.1046/j.1365-2273.1998.00133.x

Cited by 92 publications

(102 citation statements)

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“…orbital bone defects) where the restoration of the complicated anatomic structure is essential, autografts are hardly manipulated to reproduce the curvature of the local site (Borghouts & Otto 1978;Asamura et al 2010). Furthermore, resorption rates for endochondral bone have been reported up to 75 per cent (Smith & Abramson 1974) and rates of 20-30% (Vuyk & Adamson 1998) reported for membranous bone grafts. The uncontrollable and variable spontaneous resorption of autografts may compromise the precision of the restoration of orbital volume and thus potentially lead to the asymmetry of eye globes (Potter & Ellis 2004).…”

Section: Autografts and Allograftsmentioning

confidence: 99%

Biomimetic coatings for bone tissue engineering of critical-sized defects

Liu

Groot

2010

J. R. Soc. Interface.

126

119

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The repair of critical-sized bone defects is still challenging in the fields of implantology, maxillofacial surgery and orthopaedics. Current therapies such as autografts and allografts are associated with various limitations. Cytokine-based bone tissue engineering has been attracting increasing attention. Bone-inducing agents have been locally injected to stimulate the native bone-formation activity, but without much success. The reason is that these drugs must be delivered slowly and at a low concentration to be effective. This then mimics the natural method of cytokine release. For this purpose, a suitable vehicle was developed, the so-called biomimetic coating, which can be deposited on metal implants as well as on biomaterials. Materials that are currently used to fill bony defects cannot by themselves trigger bone formation. Therefore, biological functionalization of such materials by the biomimetic method resulted in a novel biomimetic coating onto different biomaterials. Bone morphogenetic protein 2 (BMP-2)-incorporated biomimetic coating can be a solution for a large bone defect repair in the fields of dental implantology, maxillofacial surgery and orthopaedics. Here, we review the performance of the biomimetic coating both in vitro and in vivo.

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Section: Autografts and Allograftsmentioning

confidence: 99%

Biomimetic coatings for bone tissue engineering of critical-sized defects

Liu

Groot

2010

J. R. Soc. Interface.

126

119

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“…Notwithstanding it still bears relative movement as complication 2 . In rhinoplasties, the operation field available to fix grafts with sutures is often times too narrow, and thus we search for a fixating material that is as cost-effective as suture wires.…”

Section: Discussionmentioning

confidence: 99%

“…The most used graft material is the autologous cartilage, with mild rates of resorption, infection and extrusion 1 . Notwithstanding, one major complication is cartilage shifting, because often times its anchorage in the nasal cavity is technically challenging 2 . Often, the inflammatory process caused by the fixating material itself facilitates both graft resorption and extrusion 3 .…”

Section: Introductionmentioning

confidence: 99%

Estudo experimental comparativo entre o butil-2-cianoacrilato, a mistura gelatina-resorcina-formaldeído e sutura na estabilização de enxertos de cartilagem em coelhos

Costa¹,

Pereira²,

Costa

et al. 2006

Rev. Bras. Otorrinolaringol.

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Cart ilage grafting is an interesting option for rinoplasties refinements. Aim: to compare butyl-2-cyanocrylate, compound gelatin-resorcin-formaldeyide (GRF) and suture control to determine the efficacy of these tissue glue preparations in securing grafted cartilage. Study Design: Experimental. Methods: Fifteen male adult New Zealand rabbits were submitted to a surgical procedure to harvest 6 auricular cartilage grafts from each animal. 2 of these grafts in each animal were glued together with butyl-2-cyanocrylate, 2 with compound gelatin-resorcin-formaldehyde and 2 sewn together with nylon suture. These sandwich grafts were then glued or sewn to the periosteum of the calvaria. After 2, 6 and 12 weeks, groups of 5 animals were sacrificed and histological analysis for inflammation was performed. Cartilage graft migration, adhesion and deformities of the grafts were also evaluated. Results: there was less migration of the cartilages glued with GRF than with cyanoacrylate and suture. There was no statistical difference between the 3 materials of graft stabilization in relation to the inflammatory reaction in all evaluated periods. There wasn't detachment neither deformity in the cartilage sandwiches sewed with suture. The majority of detachment and deformed cartilages were found among those glued with cyanoacrylate. The number of deformed cartilages was directly related to the number of detached cartilages. The data were statistically significant (p< 0.05). Conclusion: the compound gelatin-resorcin-formaldehyde revealed to be a stabilization material for cartilage grafts in rabbits better than butyl-2-cyanoacrylate. The compound gelatin-resorcin-formaldeyide was also better than the suture when comparing it's fixation to the periosteum.

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“…Autologous cartilage is the material most used for grafting, since it presents low reabsorption, infection, and extrusion degree [1]. However, one of the main complications associated with its use is displacement, and intranasal fixation is technically difficult [2]. Sometimes, the inflammatory process provoked by the fixative leads to reabsorption and extrusion [3].…”

Section: Introductionmentioning

confidence: 99%

Experimental comparative study in rabbits of three different ways of cartilage graft fixation: suture, gelatin-resorcin-formaldehyde and butyl-2-cyanoacrylate

Costa

Pereira

Costa

et al. 2007

Acta Oto-Laryngologica

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There was less migration of the cartilages glued with GRF than with cyanoacrylate and suture. GRF showed statistically less inflammatory reaction and angiogenesis than the other two methods. The three methods showed a tendency to decrease of fibrosis, inflammation, and angiogenesis as weeks passed. There was no detachment or deformity in the cartilage sandwiches sutured to the glabella's periostium. The majority of detached and deformed cartilages were those glued with cyanoacrylate. The number of detached cartilages was directly related to the number of deformed cartilages. The data were statistically significant (p<0.05).

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Biomaterials in rhinoplasty

Cited by 92 publications

References 0 publications

Biomimetic coatings for bone tissue engineering of critical-sized defects

Biomimetic coatings for bone tissue engineering of critical-sized defects

Estudo experimental comparativo entre o butil-2-cianoacrilato, a mistura gelatina-resorcina-formaldeído e sutura na estabilização de enxertos de cartilagem em coelhos

Experimental comparative study in rabbits of three different ways of cartilage graft fixation: suture, gelatin-resorcin-formaldehyde and butyl-2-cyanoacrylate

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