Biomedical Materials in Dentistry

Tabatabaei, Fahimeh; Torres, Regine; Tayebi, Lobat

doi:10.1007/978-3-030-21583-5_2

Cited by 14 publications

(12 citation statements)

References 36 publications

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“…Most recent developments include tunable conductive polymers to be used for controlled delivery [150]. As stated in Section 3.1, in tooth regeneration, drugs (such as growth factors and FGF-2) are usually simply added to the scaffold material-not yet encapsulated and released from tailored delivery materials [14,19,66,67,[151][152][153][154][155][156][157]. Recently, Moon et al reported a study using nitric oxide release to support the pulp-dentin regeneration [158].…”

Section: Drug Release Systems Useful In Tissue Engineering-to Be Adapted To Tooth Engineeringmentioning

confidence: 99%

“…Future efforts should be directed toward the development of tailored drug loading and/or encapsulation materials to be used for the controlled release of bioactive substances during tooth formation [157,173]. As shown in Figure 2 and Table 1, there are various signaling molecules and corresponding activators and suppressor molecules involved in the formation of enamel, dentin, and cementum.…”

Section: Drug Release Systems Useful In Tissue Engineering-to Be Adapted To Tooth Engineeringmentioning

confidence: 99%

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Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Baranova

Büchner

Götz

et al. 2020

IJMS

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With increasing life expectancy, demands for dental tissue and whole-tooth regeneration are becoming more significant. Despite great progress in medicine, including regenerative therapies, the complex structure of dental tissues introduces several challenges to the field of regenerative dentistry. Interdisciplinary efforts from cellular biologists, material scientists, and clinical odontologists are being made to establish strategies and find the solutions for dental tissue regeneration and/or whole-tooth regeneration. In recent years, many significant discoveries were done regarding signaling pathways and factors shaping calcified tissue genesis, including those of tooth. Novel biocompatible scaffolds and polymer-based drug release systems are under development and may soon result in clinically applicable biomaterials with the potential to modulate signaling cascades involved in dental tissue genesis and regeneration. Approaches for whole-tooth regeneration utilizing adult stem cells, induced pluripotent stem cells, or tooth germ cells transplantation are emerging as promising alternatives to overcome existing in vitro tissue generation hurdles. In this interdisciplinary review, most recent advances in cellular signaling guiding dental tissue genesis, novel functionalized scaffolds and drug release material, various odontogenic cell sources, and methods for tooth regeneration are discussed thus providing a multi-faceted, up-to-date, and illustrative overview on the tooth regeneration matter, alongside hints for future directions in the challenging field of regenerative dentistry.

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Section: Drug Release Systems Useful In Tissue Engineering-to Be Adapted To Tooth Engineeringmentioning

confidence: 99%

Section: Drug Release Systems Useful In Tissue Engineering-to Be Adapted To Tooth Engineeringmentioning

confidence: 99%

Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Baranova

Büchner

Götz

et al. 2020

IJMS

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“…Bioactive glasses dissolve when they are exposed to body fluids and then by forming the apatite crystals on their surface, they gain the ability to chemically bond with the apatite crystals which are present in bone and tooth tissues [ 8 ]. Bioactive glass has high biocompatibility and is also a type of ceramic presenting some properties of ceramics [ 9 ]. Ceramics are brittle, inorganic, and non-metallic biomaterials composed of metal-oxygen ionic bonds, and they are poor thermal conductors because they have no free electrons in their structure to transfer heat or electricity [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Bioactive glass has high biocompatibility and is also a type of ceramic presenting some properties of ceramics [ 9 ]. Ceramics are brittle, inorganic, and non-metallic biomaterials composed of metal-oxygen ionic bonds, and they are poor thermal conductors because they have no free electrons in their structure to transfer heat or electricity [ 9 ]. In addition, bioactive glass has several attractive properties including biocompatibility and antimicrobial properties that make it a suitable material for use as a scaffold in tissue engineering [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Application of bioactive glasses in various dental fields

et al. 2022

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Bioactive glasses are a group of bioceramic materials that have extensive clinical applications. Their properties such as high biocompatibility, antimicrobial features, and bioactivity in the internal environment of the body have made them useful biomaterials in various fields of medicine and dentistry. There is a great variation in the main composition of these glasses and some of them whose medical usage has been approved by the US Food and Drug Administration (FDA) are called Bioglass. Bioactive glasses have appropriate biocompatibility with the body and they are similar to bone hydroxyapatite in terms of calcium and phosphate contents. Bioactive glasses are applied in different branches of dentistry like periodontics, orthodontics, endodontics, oral and maxillofacial surgery, esthetic and restorative dentistry. Also, some dental and oral care products have bioactive glasses in their compositions. Bioactive glasses have been used as dental implants in the human body in order to repair and replace damaged bones. Other applications of bioactive glasses in dentistry include their usage in periodontal disease, root canal treatments, maxillofacial surgeries, dental restorations, air abrasions, dental adhesives, enamel remineralization, and dentin hypersensitivity. Since the use of bioactive glasses in dentistry is widespread, there is a need to find methods and extensive resources to supply the required bioactive glasses. Various techniques have been identified for the production of bioactive glasses, and marine sponges have recently been considered as a rich source of it. Marine sponges are widely available and many species have been identified around the world, including the Persian Gulf. Marine sponges, as the simplest group of animals, produce different bioactive compounds that are used in a wide range of medical sciences. Numerous studies have shown the anti-tumor, anti-viral, anti-inflammatory, and antibiotic effects of these compounds. Furthermore, some species of marine sponges due to the mineral contents of their structural skeletons, which are made of biosilica, have been used for extracting bioactive glasses.

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“…Researchers are working hard to improve the formulation of medical products available in market to meet the needs of the public. With the best of knowledge, biomaterials play a main role in the field of biomedical, as they can interact well in biological system [1,2]. Due to their unique features and wide range of applications, researchers work are still working to obtain better properties and performances of biomaterials in biomedical field [3,4].…”

Section: Introductionmentioning

confidence: 99%

A Study of Fluoride-Containing Bioglass System for Dental Materials Derived from Clam Shell and Soda Lime Silica Glass

Jalil

Матори

Zainuddin

et al. 2020

Journal of Spectroscopy

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The alumino-silicate-fluoride (ASF) bioglass system with empirical formula [(45-x)SiO2-xCaF2-20P2O5-20Al2O3-15CaO] where x = 5, 10, 15, and 20 (wt.%) has been synthesised by using conventional melt-quenching method. In this study, soda lime silica (SLS) glass and clam shell (CS) vitreous waste were utilized as a source of silicon dioxide (SiO2) and calcium oxide (CaO), respectively. The different physical behaviors of ASF bioglass were closely related to the CaF2 content in each composition. The structural analysis shows the presence of various chemical bonds showing the formation of ASF bioglass. The ASF bioglass has many applications in dental field and efforts to improve its formulation can promise a better future in medical procedures.

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Biomedical Materials in Dentistry

Cited by 14 publications

References 36 publications

Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Application of bioactive glasses in various dental fields

A Study of Fluoride-Containing Bioglass System for Dental Materials Derived from Clam Shell and Soda Lime Silica Glass

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