BioMEMS

Hosseini, Samira; Espinosa-Hernandez, Michelle Alejandra; Garcia-Ramirez, Ricardo; Cerda-Kipper, Ana Sofia; Reveles-Huizar, Sofia; Acosta-Soto, Luis

doi:10.1007/978-981-15-6382-9

Cited by 4 publications

(2 citation statements)

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“…They are based on micro/nano scale fabrication systems and help to improve the sensitivity of sensor results. It has unlabeled detection technology including microconverter, surface plasmon oscillation and organic field effect transistors [23,24].…”

Section: Biomemsmentioning

confidence: 99%

The Salivary Secretome

Perpétuo¹,

Ferreira²,

Guedes³

et al. 2023

Periodontology - New Insights

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Recently, proteomics has emerged as an important tool for understanding biological systems, protein–protein interactions, and networks that ultimately lead to a deeper understanding of the underlying mechanisms of certain diseases. More recently, the study of secretomes, a type of proteomics, has also been highlighted as a potential next step in the field of diagnosis/prognosis. The secretome is the set of proteins expressed by an organism and secreted into the extracellular space, comprising 13–20% of all proteins. Since almost all, if not all, organs produce secretomes, this means that it is possible to study secretomes and trace these proteins back to their origin, supporting the idea that this could indeed be very important in diagnosing certain diseases. This is often combined with techniques such as mass spectrometry to measure the secretome of, for example, a particular tissue, and bioinformatics tools and databases to give us an idea of what to expect (prediction). In this paper, we will give a general overview of this world, but with a focus on the new bioinformatics tools and databases, their advantages and disadvantages, as well as a deeper look at isolation systems for proteomes, specifically salivary secretomes. Indeed, the salivary secretome represents a valuable new tool capable of providing insights into immunopathology and potentially aiding in diagnostics. Furthermore, we will explore applications of these methods and give an idea of what the future holds for such promising techniques: Salivary secretome in conjunction with bioinformatics tools/databases in the diagnosis of diseases (such as diabetes, Sjogren’s syndrome, and cardiovascular disease).

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Section: Biomemsmentioning

confidence: 99%

The Salivary Secretome

Perpétuo¹,

Ferreira²,

Guedes³

et al. 2023

Periodontology - New Insights

View full text Add to dashboard Cite

show abstract

“…BioMEMS provide several benefits over traditional approaches that are worth investigating, with compact device size, mobility, replication reliability, high-throughput performance, multi-functionality, and potential automation. The smaller dimension provides apparent benefits since these devices can be miniaturized with reduced manufacturing costs for devices [7]. Furthermore, BioMEMS devices offer multi-functionality, allowing separate tools to be incorporated into a single device.…”

mentioning

confidence: 99%