Biometry of the fetal corpus callosum by three‐dimensional ultrasound

Pashaj, S.; Merz, Eberhard; Wellek, Stefan

doi:10.1002/uog.12501

Cited by 73 publications

(115 citation statements)

References 24 publications

Supporting

Mentioning

105

Contrasting

Unclassified

Order By: Relevance

“…The slice chosen for CC assessment had to accomplish strict quality criteria defined as the identification of the cavum septi pellucidi, thalamus, midbrain, cerebellar vermis and cisterna magna [27] (fig. 1).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Neurosonographic Assessment of the Corpus Callosum as Imaging Biomarker of Abnormal Neurodevelopment in Late-Onset Fetal Growth Restriction

Egaña-Ugrinovic¹,

Savchev²,

Bazán‐Arcos³

et al. 2015

Fetal Diagn Ther

View full text Add to dashboard Cite

Objective: To explore corpus callosum (CC) developmental differences by ultrasound in late-onset small fetuses compared with adequate for gestational age (AGA) controls. Study Design: Ninety four small (estimated fetal weight <10th centile) and 71 AGA fetuses were included. Small fetuses were further subdivided into fetal growth restriction (IUGR, n = 64) and small for gestational age (SGA, n = 30) based on poor perinatal outcome factors, that is, birth weight <3rd centile and/or abnormal cerebroplacental ratio and/or uterine artery Doppler. The entire cohort was scanned to assess CC by transvaginal neurosonography obtaining axial, coronal and midsagittal images. CC length, thickness, total area and the areas after a subdivision in 7 portions were evaluated by semiautomatic software. Furthermore, the weekly average growth of the CC in each study group was calculated and compared. Results: Small fetuses showed significantly shorter (small fetuses: 0.49 vs. AGA: 0.52; p < 0.01) and smaller CC (1.83 vs. 2.03; p < 0.01) with smaller splenium (0.47 vs. 0.55; p < 0.01) compared to controls. The CC growth rate was also reduced when compared to controls. Changes were more prominent in small fetuses with abnormal cerebroplacental Doppler suggesting fetal growth restriction. Conclusions: Neurosonographic assessment of CC showed significantly altered callosal development, suggesting in-utero brain reorganization in small fetuses. This data support the potential value of CC assessment by US to monitor brain development in fetuses at risk.

show abstract

Section: Methodsmentioning

confidence: 99%

“…(a) The total CC area was delineated through cursor-guided free-hand traces limited superiorly by the hyperechoic sulcus of the CC and the cingulate gyrus and inferiorly, by the cavum septi pellucidi and cavum vergae [27] (fig. 2).…”

Section: Methodsmentioning

confidence: 99%

Neurosonographic Assessment of the Corpus Callosum as Imaging Biomarker of Abnormal Neurodevelopment in Late-Onset Fetal Growth Restriction

Egaña-Ugrinovic¹,

Savchev²,

Bazán‐Arcos³

et al. 2015

Fetal Diagn Ther

View full text Add to dashboard Cite

show abstract

“…In the first trimester this can be the triplanar demonstration of a true midsagittal section which is necessary for an exact nuchal translucency (NT) measurement. 40,41 In the second and third trimesters the multiplanar display mode is helpful identifying a flat fetal profile or micrognathia 4,7,42 or pathologic brain structures like partial or completely absent corpus callosum (Figs 4A to D) 43 or slightly dilated ventricles. 7,44,45 Surface rendered images give a precise demonstration of all the defects concerning the fetal surface like in facial defects (Figs 5A and B) 4,7,[46][47][48][49][50] neural tube defects (Figs 6A and B), 7,51 abdominal defects (Fig.…”

Section: Application Of 3d/4d Sonography In Obstetricsmentioning

confidence: 99%

Current Role of 3D/4D Sonography in Obstetrics and Gynecology

Pashaj¹,

Merz²

2013

Donald School Journal of Ultrasound in Obstetrics and Gynecology

View full text Add to dashboard Cite

Modern 3D/4D sonography provides a routine method not only for storing single image planes as in 2D ultrasound but also for storing complete sets of volume data in the computer memory. Once acquisition is completed, all volumes can be accessed from the memory and normal and abnormal findings in both obstetrics and gynecology can be demonstrated in different display modes. Furthermore digital storage of volumes permits virtual examinations by reloading of volumes and navigating through them in the absence of the patient.This review article would like to give an illustration of the latest technologies in 3D/4D ultrasound in obstetrics and gynecology.

show abstract

“…Prenatal evaluation of the CC is usually performed by its visualization in the midsagittal cranial plane using 2D ultrasound. Dedicated 2D and 3D sonography or MRI are implemented in cases where CC abnormality is suspected …”

Section: Introductionmentioning

confidence: 99%

A new method for evaluating short fetal corpus callosum

et al. 2019

View full text Add to dashboard Cite

Objective Sonographic diagnosis of short corpus callosum (SCC) is based on measurement of a short for gestational age antero‐posterior length of the corpus callosum (CC) in the midsagittal plane. We suggest a new method for evaluating SCC without referring to biometry tables. Methods We measured the ratio between the CC length and the internal cranial occipitofrontal dimension (ICOFD) in the midsagittal plane in 399 normal fetuses at 20 + 6 to 35 + 3 weeks of gestation and in 31 fetuses with a diagnosis of a SCC and compared the mean ratio between two groups. The impact of cephalic biometric parameters, fetal presentation, and gender was assessed. Results The ICOFD/CC length for normal pregnancies was constant throughout the pregnancy (2.35 ± 0.11). There was no correlation between the ICOFD/CC length and cephalic index, Biparietal Diameter (BPD), head circumference, fetal sex, or fetal presentation. The ratio of pregnancies with SCC was significantly higher: 3.20 ± 0.84 (P < .0001). Conclusion The ICOFD/CC length practically does not change throughout a normal pregnancy. The ratio was significantly higher in pregnancies with SCC. Measuring this ratio during fetal anatomical scan may enable rapid evaluation of the CC without the need to refer to biometry tables.

show abstract

Biometry of the fetal corpus callosum by three‐dimensional ultrasound

Abstract: Objectives To construct reference ranges of quantitative characteristics of the fetal corpus callosum.Methods Women referred to a tertiary center for sonographic examination were recruited to undergo a detailed fetal scan from 17 to 41 weeks of gestation.

Cited by 73 publications

References 24 publications

Neurosonographic Assessment of the Corpus Callosum as Imaging Biomarker of Abnormal Neurodevelopment in Late-Onset Fetal Growth Restriction

Neurosonographic Assessment of the Corpus Callosum as Imaging Biomarker of Abnormal Neurodevelopment in Late-Onset Fetal Growth Restriction

Current Role of 3D/4D Sonography in Obstetrics and Gynecology

A new method for evaluating short fetal corpus callosum

Contact Info

Product

Resources

About