Biomimetic 3D-printed custom-made prosthesis for anterior column reconstruction in the thoracolumbar spine: a tailored option following en bloc resection for spinal tumors

Girolami, Marco; Boriani, Stefano; Bandiera, Stefano; Barbanti-Bròdano, Giovanni; Ghermandi, Riccardo; Terzi, Silvia; Tedesco, Giuseppe; Evangelisti, Gisberto; Pipola, Valerio; Gasbarrini, A.

doi:10.1007/s00586-018-5708-8

Cited by 71 publications

(59 citation statements)

References 28 publications

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“…Treatment of massive bone defects after malignant tumor resection of long bones requires meticulous surgical technique and considerable preoperative planning, especially since the treatment options are very limited. The introduction of 3D printing has broadened the scope of many medical specialties, enhanced productivity and efficiency, and allowed surgeons to meet the anatomical and physiological needs of the pathology in hand [6][7][8][9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Gürsan¹,

Celtik²,

Yanik³

et al. 2021

Cureus

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Joint-preserving prosthetic reconstruction for massive bone defects has the potential to be a new and revolutionary treatment option. In this paper, we discuss the case of a 30-year-old female patient who presented with pain and swelling around the knee for three months. The patient underwent this procedure. Postoperative patient satisfaction, pain scores, and range of motion results were found to be promising. We believe that this method has the potential to be the next stage in the quest for better treatment options for this condition.

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Section: Discussionmentioning

confidence: 99%

Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Gürsan¹,

Celtik²,

Yanik³

et al. 2021

Cureus

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“…After osteotomy and debridement in anterior column at L1, we used a 'off-the-shelf' (OTS) three-dimensional (3D) printed artificial vertebral body ( Fig. 2b-c, Beijing AK Medical Co., Ltd.) instead of various materials, such as bone grafts, mesh cages, or expandable titanium cages, to reconstruct sagittal alignment [9]. Based on preoperative 3D reconstruction of CT and MRI images, the artificial prosthesis was designed in conformity with the expected defects that may occur after the affected vertebral body resection.…”

Section: Surgical Treatmentmentioning

confidence: 99%

Intravertebral cleft in pathological vertebral fracture resulting from spinal tuberculosis: a case report and literature review

Dong

Zhu

et al. 2020

BMC Musculoskelet Disord

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Background Among common findings in osteoporotic vertebral compression fractures (OVCFs), the intravertebral cleft (IVC) is usually considered a benign lesion. The current study was aimed to present a rare case of vertebral fracture caused by IVC-related spinal tuberculosis. Case presentation A 73-year-old female complained of back pain and weakness in lower limbs for 2 weeks. 3 months ago, after a minor trauma, she got back pain without weakness in lower limbs. Initially, she was diagnosed with a L1 compression fracture and accepted conservative treatment. After an asymptomatic period, she complained progressive pain at the fracture position with weakness of both lower limbs and was referred to our hospital with suspicion of Kümmell’s disease. The patient underwent posterior debridement and internal fixation for decompression and stabilization of the spine. Pathological examinations revealed the patient with spinal tuberculosis. Conclusions Although IVC is common in patients with OCVFs, there are some cases believed to be found in patients with spinal tuberculosis or infection. Further test, like CT-guided puncture biopsy, may be required before decisive treatment when an IVC is observed.

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“…A solid vertebral body replacement (VBR) and longsegment posterior xation are needed to achieve stable spinal reconstruction and preserve spinal function [5,6] There are currently many options for VBR, which mainly depends on the axial pressure of the vertebral body and tightening force of pedicle screws for stability. VBR subsidence is the main technical complication after TES, which can lead to rod breakage and xation failure [8][9][10]. Colman carried out a TES model experiment and showed that application of a VBR with an arti cial pedicle xed to the posterior rod greatly enhanced the stability of the xation system and prevented subsidence [11].…”

Section: Introductionmentioning

confidence: 99%

Biomechanics of artificial pedicle fixation in a 3D-printed prosthesis after total en bloc spondylectomy: A finite element analysis

Wang

Ye³

et al. 2021

Preprint

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Background: This study compared the biomechanics of artificial pedicle fixation in spine reconstruction with a 3-dimensional (3D)-printed prosthesis after total en bloc spondylectomy (TES) by finite element analysis.Methods: A thoracolumbar (T10–L2) finite element model was developed and validated. Two models of T12 TES were established in combination with different fixation methods: Model A consisted of long-segment posterior fixation (T10/11, L1/2) + 3D-printed prosthesis; and Model B consisted of Model A + two artificial pedicle fixation screws. The models were evaluated with an applied of 7.5 N·m and axial force of 200 N. We recorded and analyzed the following: 1) stiffness of the two fixation systems; 2) hardware stress in the two fixation systems; and 3) stress on the endplate adjacent to the 3D-printed prosthesis.Results: The fixation strength of Model B was enhanced by the screws in the artificial pedicle, which was mainly manifested as an improvement in rotational stability. The stress transmission of the artificial pedicle fixation screws reduced the stress on the posterior rods and endplate adjacent to the 3D-printed prosthesis in all directions of motion, especially in rotation.Conclusions: After TES, the posterior long-segment fixation combined with the anterior 3D printed prosthesis could maintain postoperative spinal stability, but adding artificial pedicle fixation increased the stability of the fixation system and reduced the risk of prosthesis subsidence and instrumentation failure.

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Biomimetic 3D-printed custom-made prosthesis for anterior column reconstruction in the thoracolumbar spine: a tailored option following en bloc resection for spinal tumors

Abstract: Preliminary results from this series suggest that 3D printing can be effectively used to produce custom-made prosthesis for anterior column reconstruction. These slides can be retrieved under Electronic Supplementary Material.

Cited by 71 publications

References 28 publications

Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Three-Dimensionally-Printed Joint-Preserving Prosthetic Reconstruction of Massive Bone Defects After Malignant Tumor Resection of the Proximal Tibia

Intravertebral cleft in pathological vertebral fracture resulting from spinal tuberculosis: a case report and literature review

Biomechanics of artificial pedicle fixation in a 3D-printed prosthesis after total en bloc spondylectomy: A finite element analysis

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