Bioresorbable PPDO sliding-lock stents with optimized FDM parameters for congenital heart disease treatment

Chen, Enrong; Xiong, Zenggang; Xiao-rong, Cai; Liu, Shilong; Qin, Xiji; Sun, Jing Ping; Jin, Xuejun; Kim, Sun

doi:10.1016/j.jmbbm.2022.105609

Cited by 4 publications

(2 citation statements)

References 47 publications

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“…The Food and Drug Administration has also authorized numerous PPDO medical implants, including sutures, clips, staples, pins, and mesh [111]. A recent study explored how the temperature of the nozzle, the temperature of the bed, the thickness of the layers, and the speed of printing affect the mechanical features of PPDO stents [112]. The enhancement of Young's modulus and yield strength of PPDO FDM parts were observed with an increase in nozzle temperature and bed temperature.…”

Section: Extrusion-based 3d Printing Fused Deposition Modellingmentioning

confidence: 99%

Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents

Das,

Mehrotra,

Kumar

2023

JFB

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Coronary artery disease is the most prevalent cardiovascular disease, claiming millions of lives annually around the world. The current treatment includes surgically inserting a tubular construct, called a stent, inside arteries to restore blood flow. However, due to lack of patient-specific design, the commercial products cannot be used with different vessel anatomies. In this review, we have summarized the drawbacks in existing commercial metal stents which face problems of restenosis and inflammatory responses, owing to the development of neointimal hyperplasia. Further, we have highlighted the fabrication of stents using biodegradable polymers, which can circumvent most of the existing limitations. In this regard, we elaborated on the utilization of new fabrication methodologies based on additive manufacturing such as three-dimensional printing to design patient-specific stents. Finally, we have discussed the functionalization of these stent surfaces with suitable bioactive molecules which can prove to enhance their properties in preventing thrombosis and better healing of injured blood vessel lining.

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Section: Extrusion-based 3d Printing Fused Deposition Modellingmentioning

confidence: 99%

Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents

Das,

Mehrotra,

Kumar

2023

JFB

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“…This includes temperature, layer thickness, angle, and fill pattern [ 8 , 9 ]. Optimizing these parameters is essential for attaining the desired mechanical, thermal, or other properties [ 10 , 11 ]. At the same time, the production of customized filaments poses a number of difficulties and print quality issues.…”

Section: Introductionmentioning

confidence: 99%

Optimization of Printing Process Variables and the Effect of Post-Heat Treatments on the Mechanical Properties of Extruded Polylactic Acid–Aluminum Composites

Ganapathy,

Sakthivel,

Kandasamy

et al. 2023

Polymers

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Polymer extrusions are employed in the fabrication of crucial parts for automotive, aerospace, and other mechanical applications. The use of fillers and microfibers is contributing to the advancement of material extrusion polymers. In order to enhance their mechanical characteristics, printed materials undergo a post-heating process utilizing microwaves. Specimens were fabricated using polylactic acid filaments containing 2 wt% aluminum. Two sets of specimens were fabricated and subjected to testing in order to evaluate the features of extruded specimens and specimens that underwent post-heating. In terms of mechanical performance, specimens subjected to post-heating exhibited superior results compared to specimens merely subjected to extrusion. The tensile, flexural, and Shore D hardness properties of the specimens exhibited improvements of 5.07, 6.16, and 1.32%, respectively, after being subjected to heating. Furthermore, the wear rate decreased by 13.58 percent. The results of the regression analysis indicate that the print angle and the air gap exhibit the greatest influence on the observed responses. The validation test outcomes exhibit a high level of concordance with the predicted findings. The mechanical and surface properties of components extruded with filler-added material are enhanced by subsequent heating.

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Effect of Printing Parameters on Mechanical Properties and Dimensional Accuracy of 316L Stainless Steel Fabricated by Fused Filament Fabrication

Wang,

Mai,

Shi

et al. 2023

J. of Materi Eng and Perform

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Bioresorbable PPDO sliding-lock stents with optimized FDM parameters for congenital heart disease treatment

Cited by 4 publications

References 47 publications

Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents

Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents

Optimization of Printing Process Variables and the Effect of Post-Heat Treatments on the Mechanical Properties of Extruded Polylactic Acid–Aluminum Composites

Effect of Printing Parameters on Mechanical Properties and Dimensional Accuracy of 316L Stainless Steel Fabricated by Fused Filament Fabrication

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