Biosensors based on cholinesterases for the analysis of pesticides, heavy metal ions and hypochlorite species

Soldatkin, A. P.

doi:10.7124/bc.0004b4

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Biosensors based on ENFETs and inhibition phenomena have been designed for determination of different toxic components [51,52,53,54,55,56,57,58,59,60]. The main analytical characteristics of such biosensors are presented in Table 2.…”

Section: Enfets Based On Inhibitory Analysismentioning

confidence: 99%

Biosensors based on enzyme field-effect transistors for determination of some substrates and inhibitors

Dzyadevych

Солдаткин

Korpan

et al. 2003

Analytical and Bioanalytical Chemistry

View full text Add to dashboard Cite

This paper is a review of the authors' publications concerning the development of biosensors based on enzyme field-effect transistors (ENFETs) for direct substrates or inhibitors analysis. Such biosensors were designed by using immobilised enzymes and ion-selective field-effect transistors (ISFETs). Highly specific, sensitive, simple, fast and cheap determination of different substances renders them as promising tools in medicine, biotechnology, environmental control, agriculture and the food industry. The biosensors based on ENFETs and direct enzyme analysis for determination of concentrations of different substrates (glucose, urea, penicillin, formaldehyde, creatinine, etc.) have been developed and their laboratory prototypes were fabricated. Improvement of the analytical characteristics of such biosensors may be achieved by using a differential mode of measurement, working solutions with different buffer concentrations and specific agents, negatively or positively charged additional membranes, or genetically modified enzymes. These approaches allow one to decrease the effect of the buffer capacity influence on the sensor response in an aim to increase the sensitivity of the biosensors and to extend their dynamic ranges. Biosensors for the determination of concentrations of different toxic substances (organophosphorous pesticides, heavy metal ions, hypochlorite, glycoalkaloids, etc.) were designed on the basis of reversible and/or irreversible enzyme inhibition effect(s). The conception of an enzymatic multibiosensor for the determination of different toxic substances based on the enzyme inhibition effect is also described. We will discuss the respective advantages and disadvantages of biosensors based on the ENFETs developed and also demonstrate their practical application.

show abstract

Section: Enfets Based On Inhibitory Analysismentioning

confidence: 99%

Biosensors based on enzyme field-effect transistors for determination of some substrates and inhibitors

Dzyadevych

Солдаткин

Korpan

et al. 2003

Analytical and Bioanalytical Chemistry

View full text Add to dashboard Cite

show abstract

Biosensors based on ion-selective field effect transistors: theory, technology, practice

Dzyadevych

2004

Biopolym. Cell

View full text Add to dashboard Cite

Рассматриваются основные теоретические принципы, лежащие в основе работы ионоселективных полевых транзисторов и их применения в биоаналитической, практике. Приведены некоторые особенности наиболее продвинутых микротехнологий для их изготовления, схемы измерений с сопутствующим аппаратным обеспечением. Детально описаны достижения в области разработки ферментных биосенсоров на основе ионоселективных полевых транзисторов и оценены перспекти вы их использования.

show abstract

Biosensors based on cholinesterases for the analysis of pesticides, heavy metal ions and hypochlorite species

Cited by 2 publications

References 9 publications

Biosensors based on enzyme field-effect transistors for determination of some substrates and inhibitors

Biosensors based on enzyme field-effect transistors for determination of some substrates and inhibitors

Biosensors based on ion-selective field effect transistors: theory, technology, practice

Contact Info

Product

Resources

About