Biosensors exploiting unconventional platforms: The case of plasmonic light-diffusing fibers

Power Coupling Between Light Diffusing Fibers: Modelling and Validation

“…L IGHT diffusing optical fibers (LDFs) exploitation is currently of great interest [1]- [5]. These fibers have been designed and employed mainly for lighting or light delivery in biomedical applications [1]- [2].…”

“…These fibers have been designed and employed mainly for lighting or light delivery in biomedical applications [1]- [2]. More recently, these fibers have been used for efficient disinfection [3], for optical communications [4] and sensing applications [5].…”

Cost-Effective Fiber Optic Solutions for Biosensing

“…In LDF, the light is not confined to the core; on the contrary, it is diffused on the external medium all along their length. Thus, Cennamo et al have used this aspect to excite the plasmonic phenomenon on metal nano-films deposited on the LDF [ 70 , 71 , 72 , 73 , 74 ]. In particular, this type of SPR sensor can be produced using silica [ 70 , 71 ] or polymer [ 72 ] by coating the fiber with metal nano-films, such as gold [ 70 , 72 ] or silver [ 71 ], by sputtering.…”

“…This aspect allows an easier fabrication procedure since only a metal deposition step is required to build the SPR sensor. Moreover, SPR sensors based on silica LDF have already demonstrated high performances in bio/chemical sensing applications, as reported in [ 73 ], when the SPR–LDF probe is combined with a bioreceptor (e.g., antibody). For instance, Figure 9 a shows an outline of a SPR sensor system based on a silica LDF covered by gold nano-film connected to a white light source and a spectrometer [ 70 ].…”

Label-free plasmonic-based biosensing using a gold nanohole array chip coated with a wafer-scale deposited WS2monolayer

“…However, because we only used 1 mL of solution for each measurement, the LOD can be expressed simply by the number of captured beads for this analyte volume, resulting in the corresponding values of 10 6 PS beads per mL and 7.46 × 10 6 PS beads per mL, respectively. To compare these performances with the typical responses of other SPR biosensors, Table ST2 in the ESI le † compares LOD values reported in literature [41][42][43][44] for different plasmonic sensors functionalized with different receptors for specic detection of various substances with RI and size similar to those of the PS beads (75 nm in diameter and RI = 1.59) used in this work. We also measured the SPR transmission intensity, full width at half maximum (FWHM) of the spectral peak, and detection sensitivity of different sensors.…”