Biosynthesis of TiO2 Nanoparticles Using Edible Mushroom (Pleurotus djamor) Extract: Mosquito Larvicidal, Histopathological, Antibacterial and Anticancer Effect

Manimaran, Kumar; Murugesan, Subban; Ragavendran, Chinnasamy; Balasubramani, Govindasamy; Ganesan, Abirami Ramu; Seedevi, Palaniappan

doi:10.1007/s10876-020-01888-3

Cited by 28 publications

(15 citation statements)

References 44 publications

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“…It was reported that in a filter paper assay, Trichoderma viride -mediated TiO 2 NPs (100 ppm) showed significant biopesticidal activity and enhanced the mortality rate of H. armigera up to 100%, while they did not exhibit any toxic effect against Eudrilus eugeniae (earthworm) [ 177 ]. Recently, the anticancer and antibacterial activity of TiO 2 NPs synthesized using Pleurotus djamor (an edible mushroom) has been studied, and it has been reported that TiO 2 NPs (31 nm) showed strong anticancer activity against A549 cancer cells and significant antibacterial activity against C. diphtheria , S. aureus and P. fluorescens [ 178 ]. IONPs have immense capabilities in biomedicine, environment, life science, agriculture, biosensors and storage [ 179 ].…”

Section: Fungi- and Yeast-mediated Biosynthesis Of Nanoparticlesmentioning

confidence: 99%

Microbe-Mediated Biosynthesis of Nanoparticles: Applications and Future Prospects

et al. 2021

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Nanotechnology is the science of nano-sized particles/structures (~100 nm) having a high surface-to-volume ratio that can modulate the physical, chemical and biological properties of the chemical compositions. In last few decades, nanoscience has attracted the attention of the scientific community worldwide due to its potential uses in the pharmacy, medical diagnostics and disease treatment, energy, electronics, agriculture, chemical and space industries. The properties of nanoparticles (NPs) are size and shape dependent. These characteristic features of nanoparticles can be explored for various other applications such as computer transistors, chemical sensors, electrometers, memory schemes, reusable catalysts, biosensing, antimicrobial activity, nanocomposites, medical imaging, tumor detection and drug delivery. Therefore, synthesizing nanoparticles of desired size, structure, monodispersity and morphology is crucial for the aforementioned applications. Recent advancements in nanotechnology aim at the synthesis of nanoparticles/materials using reliable, innoxious and novel ecofriendly techniques. In contrast to the traditional methods, the biosynthesis of nanoparticles of a desired nature and structure using the microbial machinery is not only quicker and safer but more environmentally friendly. Various microbes, including bacteria, actinobacteria, fungi, yeast, microalgae and viruses, have recently been explored for the synthesis of metal, metal oxide and other important NPs through intracellular and extracellular processes. Some bacteria and microalgae possess specific potential to fabricate distinctive nanomaterials such as exopolysaccharides, nanocellulose, nanoplates and nanowires. Moreover, their ability to synthesize nanoparticles can be enhanced using genetic engineering approaches. Thus, the use of microorganisms for synthesis of nanoparticles is unique and has a promising future. The present review provides explicit information on different strategies for the synthesis of nanoparticles using microbial cells; their applications in bioremediation, agriculture, medicine and diagnostics; and their future prospects.

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Section: Fungi- and Yeast-mediated Biosynthesis Of Nanoparticlesmentioning

confidence: 99%

Microbe-Mediated Biosynthesis of Nanoparticles: Applications and Future Prospects

et al. 2021

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“…The intensity of the color of the extract was determined at the wavelength of 345 nm. The synthesized TiO 2 NPs formed, spherical in shape, with sizes of 31 nm [ 44 ].…”

Section: Different Types Of Nanoparticles Derived From Oyster Mushmentioning

confidence: 99%

“…After that, Debnath et al (2019) also fabricated AgNPs from Pleurotus giganteus and analyzed their antibacterial activity [ 51 ]. The TiO 2 NPs mediated from extract of P. djamor exhibited significant bactericidal activity against human pathogenic bacteria with maximum zone of inhibition P. fluorescens (33 ± 0.2 mm), Corynebacterium diphtheria (32 ± 0.1 mm), S. aureus (32 ± 0.4 mm), and showed higher levels of the inhibitory effect [ 44 ]. The P. djamor ZnONPs showed a maximum zone of inhibition against C. diphtheriae (28.6 ± 0.3 mm), P. fluorescens (27 ± 0.5 mm), and S. aureus (26.6 ± 1.5 mm) [ 43 ].…”

Section: Applications Of Pleurotus Derived Nanoparticlesmentioning

confidence: 99%

“…The study revealed that the green synthesized AgNPs showed high antiproliferative activity in contrast to other PS extract and Au NPs, and the reason behind the mechanism was due to the generation of more ROS, leading to oxidative stress, resulting in undeviated damage of protein functionality and integrity [ 60 ]. The anticancer activity of TiO 2 NPs showed potential toxic effect against human lung cancer (A549) cell lines with maximum inhibited growth of 64% at concentration of 100 µg/mL, after 24 h of exposure [ 44 ]. The anticancer activity evaluated from P. djamor ZnONPs showed potent inhibitory on A549 cancerous cells with (LC50(Lethal concentration required to kill 50% of population) value as 42.26 µg/mL) in a dose-dependent manner [ 43 ].…”

Section: Applications Of Pleurotus Derived Nanoparticlesmentioning

confidence: 99%

“…aegypti and Cx. quinquefasciatus resulted in larvicidal activity with LC50 (5.88 and 4.84 µg/L) and LC90 (22.80 and 19.33 µg/L) [ 44 ]. The Ae.…”

Section: Applications Of Pleurotus Derived Nanoparticlesmentioning

confidence: 99%

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Pleurotus Macrofungi-Assisted Nanoparticle Synthesis and Its Potential Applications: A Review

Bhardwaj

Sharma

Tejwan

et al. 2020

JoF

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Research and innovation in nanoparticles (NPs) synthesis derived from biomaterials have gained much attention due to their unique characteristics, such as low-cost, easy synthesis methods, high water solubility, and eco-friendly nature. NPs derived from macrofungi, including various mushroom species, such as Agaricus bisporus, Pleurotus spp., Lentinus spp., and Ganoderma spp. are well known to possess high nutritional, immune-modulatory, antimicrobial (antibacterial, antifungal and antiviral), antioxidant, and anticancerous properties. Fungi have intracellular metal uptake ability and maximum wall binding capacity; because of which, they have high metal tolerance and bioaccumulation ability. Primarily, two methods have been comprehended in the literature to synthesize metal NPs from macrofungi, i.e., the intracellular method, which refers to NP synthesis inside fungal cells by transportation of ions in the presence of enzymes; and the extracellular method, which refers to the treatment of fungal biomolecules aqueous filtrate with a metal precursor. Pleurotus derived metal NPs are known to inhibit the growth of numerous foodborne pathogenic bacteria and fungi. To the best of our knowledge, there is no such review article reported in the literature describing the synthesis and complete application and mechanism of NPs derived from macrofungi. Herein, we intend to summarize the progressive research on macrofungi derived NPs regarding their synthesis as well as applications in the area of antimicrobial (antibacterial & antifungal), anticancer, antioxidant, catalytic and food preservation. Additionally, the challenges associated with NPs synthesis will also be discussed.

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Investigation of the Apoptotic and Antimetastatic Effects of Nano‐Niosomes Containing the Plant Extract Anabasis setifera on HeLa: In Vitro Cervical Cancer Study

Ebadi,

Kavousi,

Farahmand

2024

Chemistry & Biodiversity

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The present study focuses on the preparation of niosomes containing an extract of Anabasis setifera&evaluates their efficacy in inhibiting the growth&proliferation of HeLa.Thin‐layer hydration technique was used to prepare niosomes/extract nanoparticles(NPs).The physicochemical properties of the synthesized NPs were confirmed by SEM,DLS,zeta potential analysis&FTIR.The cytotoxicity of free extract,free niosome&NPs was investigated by MTTassay.For this purpose,solutions of the three mentioned agents were prepared&diluted in 400,200,100,50,25,12.5&6.25µg/ml concentrations&incubated for24,48&72 hours.After calculating the IC50 concentration&treating the cells with this concentration,Real‐time‐PCR(to measure changes in the expression of apoptosis and metastasis genes),flowcytometry(to determine the amount of early and late induced apoptosis)&cellcycle test(to determine the stopping stage of the cancer cell division cycle)were performed.Also,the scratch test(The ability to inhibit cell metastasis after treatment)was used to evaluate cell migration.The MTTassay results showed that 72hours of treatment with NPs has the greatest effect on the death of cancer cells.Real‐time PCR showed that the expression of the Bad gene increased dramatically and the expression of the BCL‐XL,ITGA5&ZEB‐1 decreased significantly.The flowcytometry results showed that 48.64% of HeLa cells underwent apoptosis after treatment with synthesized NPs.The scratch test results showed that cancer cell metastasis stopped after treatment with NPs.The research demonstrates the significant potential of NPs,as highly efficient drug carriers for cancer therapy

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Biosynthesis of TiO2 Nanoparticles Using Edible Mushroom (Pleurotus djamor) Extract: Mosquito Larvicidal, Histopathological, Antibacterial and Anticancer Effect

Cited by 28 publications

References 44 publications

Microbe-Mediated Biosynthesis of Nanoparticles: Applications and Future Prospects

Microbe-Mediated Biosynthesis of Nanoparticles: Applications and Future Prospects

Pleurotus Macrofungi-Assisted Nanoparticle Synthesis and Its Potential Applications: A Review

Investigation of the Apoptotic and Antimetastatic Effects of Nano‐Niosomes Containing the Plant Extract Anabasis setifera on HeLa: In Vitro Cervical Cancer Study

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