Biotechnological Applications of Cold‐Adapted Bacteria

García-Descalzo, L.; Alcázar, Alberto; Baquero, Fernando; Cid, Cristina

doi:10.1002/9781118394144.ch6

Cited by 8 publications

(9 citation statements)

References 29 publications

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“…Although preliminary studies have suggested little to no increased risk of cancer incidence in patients with psoriasis receiving these therapies, further study allowing greater follow-up and increased power is required to properly examine the potential cancer risk, particularly for sitespecific cancers. 69 In contrast to this, the association between phototherapy in psoriasis and cancer incidence has been extensively explored, with an increased risk of squamous cell carcinoma and basal cell carcinoma being well established. 9 Furthermore, the increased prevalence of known cancer risk factors in people with psoriasis, such as smoking, excessive alcohol consumption, and obesity, has also been posited as a plausible explanation for an association with cancer.…”

Section: Discussionmentioning

confidence: 99%

Association of Psoriasis With the Risk of Developing or Dying of Cancer

et al. 2019

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IMPORTANCEThe risk of cancer developing in people with psoriasis has raised some concern, with little clarity regarding differentiation in risk according to psoriasis severity. OBJECTIVE To conduct a systematic review and meta-analysis of observational studies on the risk of cancer incidence and mortality in people with psoriasis.DATA SOURCES Six electronic databases (MEDLINE, Embase, MEDLINE in Process, Cochrane Central Register, Web of Science, and LILACS [Literatura Latino-Americana e do Caribe em Ciências da Saúde]) were searched from inception to November 15, 2017, for eligible studies.STUDY SELECTION Cohort and case-control studies that provided estimates of the risk of cancer incidence or cancer mortality associated with psoriasis were included.DATA EXTRACTION AND SYNTHESIS Data were extracted relating to study design, study population, and risk estimates. Study-specific estimates of the relative risk (RR) were combined using a random-effects model. Heterogeneity was quantified using the I 2 statistic.

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Section: Discussionmentioning

confidence: 99%

Association of Psoriasis With the Risk of Developing or Dying of Cancer

et al. 2019

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“…This "fishy" aroma could generalize associations with fish spoilage and have significant adverse effects on the marine fish consumption. S. putrefaciens is a cold-adapted microorganism in refrigerated marine fish, and cold-adapted microorganisms exhibit many unique characteristics and molecular mechanisms that allow them to adapt to the environment [33,34]. Low temperature presents many challenges for cold-adapted microorganisms to grow at low temperature, including the increased liquid water viscosity, decreased enzyme activity, reduced lipid membranes' fluidity, enhanced the stability of inhibiting nucleic acid structure, and disturbed protein conformation [35][36][37][38].…”

Section: Introductionmentioning

confidence: 99%

Quantitative Analysis of Cold Stress Inducing Lipidomic Changes in Shewanella putrefaciens Using UHPLC-ESI-MS/MS

et al. 2019

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Shewanella putrefaciens is a well-known specific spoilage organism (SSO) and cold-tolerant microorganism in refrigerated fresh marine fish. Cold-adapted mechanism includes increased fluidity of lipid membranes by the ability to finely adjust lipids composition. In the present study, the lipid profile of S. putrefaciens cultivated at 30, 20, 10, 4, and 0 °C was explored using ultra-high-pressure liquid chromatography/electrospray ionization tandem mass spectrometry (UHPLC-ESI-MS/MS) to discuss the effect of lipid composition on cold-adapted tolerance. Lipidomic analysis detected a total of 27 lipid classes and 606 lipid molecular species in S. putrefaciens cultivated at 30, 20, 10, 4, and 0 °C. S. putrefaciens cultivated at 30 °C (SP-30) had significantly higher content of glycerolipids, sphingolipids, saccharolipids, and fatty acids compared with that at 0 °C (SP-0); however, the lower content of phospholipids (13.97%) was also found in SP-30. PE (30:0), PE (15:0/15:0), PE (31:0), PA (33:1), PE (32:1), PE (33:1), PE (25:0), PC (22:0), PE (29:0), PE (34:1), dMePE (15:0/16:1), PE (31:1), dMePE (15:1/15:0), PG (34:2), and PC (11:0/11:0) were identified as the most abundant lipid molecular species in S. putrefaciens cultivated at 30, 20, 10, 4, and 0 °C. The increase of PG content contributes to the construction of membrane lipid bilayer and successfully maintains membrane integrity under cold stress. S. putrefaciens cultivated at low temperature significantly increased the total unsaturated liquid contents but decreased the content of saturated liquid contents.

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“…Sulfated heteropolysaccharide [11] Pseudoalteromonas sp. Linear arrangement of α-(1-6) linkage of glucose with a high degree of acetylation [12,13] Psychrobacter arcticus Peptidoglycan [14] Psychrobacter frigidicola Peptidoglycan [15] Colwellia psychrerythraea N-acetyl quinovosamine and galacturonic acid [16,17]…”

Section: Microorganism Biomolecules Referencesmentioning

confidence: 99%

Identification of Biomolecules Involved in the Adaptation to the Environment of Cold-Loving Microorganisms and Metabolic Pathways for Their Production

2021

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Cold-loving microorganisms of all three domains of life have unique and special abilities that allow them to live in harsh environments. They have acquired structural and molecular mechanisms of adaptation to the cold that include the production of anti-freeze proteins, carbohydrate-based extracellular polymeric substances and lipids which serve as cryo- and osmoprotectants by maintaining the fluidity of their membranes. They also produce a wide diversity of pigmented molecules to obtain energy, carry out photosynthesis, increase their resistance to stress and provide them with ultraviolet light protection. Recently developed analytical techniques have been applied as high-throughoutput technologies for function discovery and for reconstructing functional networks in psychrophiles. Among them, omics deserve special mention, such as genomics, transcriptomics, proteomics, glycomics, lipidomics and metabolomics. These techniques have allowed the identification of microorganisms and the study of their biogeochemical activities. They have also made it possible to infer their metabolic capacities and identify the biomolecules that are parts of their structures or that they secrete into the environment, which can be useful in various fields of biotechnology. This Review summarizes current knowledge on psychrophiles as sources of biomolecules and the metabolic pathways for their production. New strategies and next-generation approaches are needed to increase the chances of discovering new biomolecules.

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Biotechnological Applications of Cold‐Adapted Bacteria

Cited by 8 publications

References 29 publications

Association of Psoriasis With the Risk of Developing or Dying of Cancer

Association of Psoriasis With the Risk of Developing or Dying of Cancer

Quantitative Analysis of Cold Stress Inducing Lipidomic Changes in Shewanella putrefaciens Using UHPLC-ESI-MS/MS

Identification of Biomolecules Involved in the Adaptation to the Environment of Cold-Loving Microorganisms and Metabolic Pathways for Their Production

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