Bisphenol A Influences the Plasma Calcium Level and Inhibits Calcitonin Secretion in Goldfish

Suzuki, Nobuo; Kambegawa, Akira; Hattori, Atsuhiko

doi:10.2108/zsj.20.745

Cited by 25 publications

(14 citation statements)

References 26 publications

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“…Environmental hormone bisphenol-A (2,2-bis(4-hydroxyphenyl) propane, BPA) has varying different adverse effects toward organisms, such as fish [1], rats [2], and human health [3]. A number of countries and regions, including China [4], San Francisco [5], Canada, and the European Union [6], have issued policies banning BPA in products in response to the adverse effects of BPA.…”

Section: Introductionmentioning

confidence: 99%

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in the Surface Water from a Water Diversion Project in Nanjing, China

Zheng

Liu

Ren

et al. 2019

IJERPH

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Due to the widespread use of bisphenol analogues (BPs) as alternatives to bisphenol A (BPA), considerable attention for health risk has been shown in aquatic ecosystems. The occurrence and distribution of six BPs were researched in a soluble phase (<10−3 μm), colloidal phase (10−3 μm to 1 µm), and suspended particulate matter (SPM >1 µm) in a water diversion project of Nanjing, China. Except for bisphenol Z, all BPs were detected in two or three phases, where the total concentrations of detected BPs were 161–613 ng/L, 5.19–77.2 ng/L, and 47.5–353 ng/g for the soluble phase, colloidal phase, and SPM, respectively. Among the detected compounds, BPA is still the dominant BPs in the soluble and colloidal phases, which is followed by bisphenol-S , while bisphenol-AF was the major contaminant in SPM, followed by BPA. The mean contribution proportions of colloids were 1–2 orders of magnitude higher than SPM, which suggests that colloids have a clear impact on regulating BPs’ environmental behaviors. In terms of spatial distribution, the water diversion project could reduce the pollution levels of BPs, which might further affect the ecological security of the Yangtze River.

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Section: Introductionmentioning

confidence: 99%

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in the Surface Water from a Water Diversion Project in Nanjing, China

Zheng

Liu

Ren

et al. 2019

IJERPH

View full text Add to dashboard Cite

show abstract

“…Environmental hormone bisphenol-A (2,2-bis(4-hydroxyphenyl)propane; BPA) has varying degrees of influence on animals, such as fish [1], rats [2] and human health [3]. A number of countries and regions, including China [4], San Francisco [5], Canada and European Union [6], have issued policies banning BPA in products in response to the adverse effects of BPA.…”

Section: Introductionmentioning

confidence: 99%

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in The Surface Water from A Water Diversion Project in Nanjing, China

Zheng¹,

Liu²,

Ren³

et al. 2019

Preprint

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Because of the widespread use of bisphenol analogues (BPs) as the alternatives to bisphenol A (BPA), they have attracted considerable attention for health risk in aquatic ecosystems. The occurrence and distribution of six BPs were researched in soluble phase (< 5 kDa), colloidal phase (5 kDa to 1 µm) and suspended particulate matter (SPM > 1 µm) in a water diversion project of Nanjing, China. Except for bisphenol Z, all BPs were detected in the two or three phases, the total concentrations of detected BPs were 161-613 ng/L, 5.19-77.2 ng/L and 47.5-353 ng/g for the soluble phase, colloidal phase and SPM, respectively. Among the detected compounds, BPA still the dominant BPs in the soluble and colloidal phases, followed by BPS, while BPAF was the major contaminant in SPM, followed by BPA. The mean contribution proportions of colloids were 1-2 orders of magnitude higher than SPM, suggesting that colloids have an obvious impact on regulating BPs’ environmental behaviors. In terms of spatial distribution, although the water diversion project could reduce the pollution levels of BPs, which might further affect the ecological security of the Yangtze River.

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“…However, it was thought that BPA produced various effects through multifactorial pathways on bone cells including osteoblasts and osteoclasts (Miki et al, 2016). Suzuki et al (2003b) investigated how BPA affects plasma calcium and calcitonin levels in goldfish. Goldfish aquarium waters were mixed with 10 À6 M BPA.…”

Section: Discussionmentioning

confidence: 99%

Impact of prenatal exposure to bisphenol A on pregnant rats: Fetal bone development and immunohistochemistry implications

et al. 2019

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Background: Bisphenol A (BPA) is one of the most commonly produced chemicals in the world. BPA is used in products such as food packaging, personal care products, detergents, and plastic bottles. This study was conducted to determine the effect of BPA on fetal bone development. Material and methods: In this study, 16 pregnant female Sprague-Dawley rats were used. The rats were divided into four groups: the control group and 0.5 mg/kg/day, 5 mg/kg/day, and 50 mg/kg/day dose BPA groups. The skeletal system development of fetuses was examined with double skeletal and immunohistochemistry (IHC) staining (tartrate resistant acid phosphatase (TRAP) and the alkaline phosphatase (AP) expressions) methods. Results: The highest ossification rates in the humerus, radius, and ulna were detected as 41.05%, 39.25%, and 37.26% in the control group, respectively. The highest ossification rates in the femur, tibia, and fibula were detected as 23.04%, 30.73%, and 32.78% in the control group, respectively. Statistically significant differences were found between control and experimental groups in the TRAP and AP expression of the femur by IHC staining (p < 0.001). Conclusion: Exposure to BPA during pregnancy adversely affected ossification and bone growth. A dosedependent decrease was observed in the rate of ossification.

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Bisphenol A Influences the Plasma Calcium Level and Inhibits Calcitonin Secretion in Goldfish

Cited by 25 publications

References 26 publications

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in the Surface Water from a Water Diversion Project in Nanjing, China

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in the Surface Water from a Water Diversion Project in Nanjing, China

Occurrence, Distribution and Ecological Risk of Bisphenol Analogues in The Surface Water from A Water Diversion Project in Nanjing, China

Impact of prenatal exposure to bisphenol A on pregnant rats: Fetal bone development and immunohistochemistry implications

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