Encyclopedia of Bone Biology 2020
DOI: 10.1016/b978-0-12-801238-3.11261-9
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Bisphosphonates and Bone Cells—Molecular Mechanisms

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“…Alendronate sodium, as a nitrogen-containing bisphosphonate, is an effective drug for the treatment of osteoporosis. , It has a good affinity to bind with hydroxyapatite in bone and has a strong chelating effect with Ca 2+ ions in hydroxyapatite and can inhibit the activity of osteoclasts. , Ma et al reported alendronate-doped hydroxyapatite synthesized by the conventional co-precipitation method for an efficient removal of heavy-metal contaminants.…”
Section: Introductionmentioning
confidence: 99%
“…Alendronate sodium, as a nitrogen-containing bisphosphonate, is an effective drug for the treatment of osteoporosis. , It has a good affinity to bind with hydroxyapatite in bone and has a strong chelating effect with Ca 2+ ions in hydroxyapatite and can inhibit the activity of osteoclasts. , Ma et al reported alendronate-doped hydroxyapatite synthesized by the conventional co-precipitation method for an efficient removal of heavy-metal contaminants.…”
Section: Introductionmentioning
confidence: 99%