2024
DOI: 10.3389/frtra.2024.1309927
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BK polyomavirus infection: more than 50 years and still a threat to kidney transplant recipients

Sandesh Parajuli,
Fahad Aziz,
Weixiong Zhong
et al.

Abstract: BK polyomavirus (BKPyV) is a ubiquitous human polyomavirus and a major infection after kidney transplantation, primarily due to immunosuppression. BKPyV reactivation can manifest as viruria in 30%–40%, viremia in 10%–20%, and BK polyomavirus-associated nephropathy (BKPyVAN) in 1%–10% of recipients. BKPyVAN is an important cause of kidney graft failure. Although the first case of BKPyV was identified in 1971, progress in its management has been limited. Specifically, there is no safe and effective antiviral age… Show more

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