2020
DOI: 10.21203/rs.3.rs-27734/v1
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BK polyomavirus infection promotes growth and aggressiveness in bladder cancer

Abstract: Background Recent studies have confirmed the integration of the BK polyomavirus (BKPyV) gene into the cellular genome of urothelial carcinomas in transplant recipients, further confirming the correlation between BKPyV and urothelial carcinomas after transplantation. However, the role BKPyV infections play in the biological function of bladder cancer remains unclear.Methods We developed a BKPyV-infected bladder cancer cell model and a mice tumor model to discuss the role of BKPyV infections.Results Our research… Show more

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