Bladder cancer in patients with spina bifida: a serious risk

Mühlbauer, Julia; Stein, Raimund; Younsi, Nina

doi:10.1007/s00345-020-03338-1

Cited by 7 publications

(1 citation statement)

References 25 publications

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“…The approximate percentage of the squamous component should be noted in the report. Squamous differentiation may be seen in the context of chronic irritation such as with stones, Schistosoma infection and neurogenic bladder with in-dwelling catheters (39,40). Human papilloma virus (HPV) is not thought to be a causative agent of this divergent morphology.…”

Section: Urothelial Carcinoma With Squamous Differentiationmentioning

confidence: 99%

Invasive Urothelial Carcinoma: Subtypes and Divergent Differentiation

Downes

2022

Urologic Cancers

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Invasive urothelial carcinoma is the most frequent type of bladder cancer and may occur in pure or classical form or with the presence of variant or subtype histology and/or evidence of divergent morphology such as squamous, glandular, or trophoblastic differentiation. Increasingly, it is recognized that certain subtypes impact patient prognosis and outcome hence the need to correctly recognize and document their presence. Certain subtypes and divergent features correlate with the emerging molecular bladder cancer subtypes, which can also influence patient management decisions. The pathologist therefore plays a crucial role in providing clinically relevant information, mostly derived from hematoxylin and eosin slides, which will guide urologists and oncologists in terms of risk stratification and treatment planning.

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Section: Urothelial Carcinoma With Squamous Differentiationmentioning

confidence: 99%