Bladder cancer prevention

Długosz, Anna; Królik, Ewelina

doi:10.5603/njo.2017.0040

Cited by 1 publication

(1 citation statement)

References 60 publications

(80 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other studies claimed a drop in the frequency rate of bladder cancer related to the successful control of Schistosomiasis [25], [28]. Worth mentioning, some research studies have omitted S. hematobium from epidemiology and bladder cancer prevention [29].…”

Section: Introductionmentioning

confidence: 99%

Schistosomiasis and Bladder Cancer in Egypt: Truths and Myths

Amin

Kobaisi²,

Samir

2019

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: The gathered archeopathological evidence has confirmed that Schistosomiasis has been endemic in Ancient Egypt for over 500 decades. The association between Schistosoma hematobium and increase bladder cancer risk is also well acknowledged. However, over the years, there is a proved changing pattern of bladder cancer that needs to be investigated. AIM: We aim to discuss the truths and myths about bladder cancer and its association with Schistosomiasis in Egypt. METHODS: A cross-sectional, case-control study was performed to collect recent data on the topic. RESULTS: Of the reported cancer cases, 79.3% were transitional cell carcinoma (TCC), an additional 6% showed associated squamous features. Squamous cell carcinoma (SCC) constituted only 13.8% of cancer cases. Schistosomiasis was histologically confirmed in 19 cancer cases, only one was SCC. The relative frequency of TCC is increasing, while SCC is decreasing. There is no evidence that this pattern is related to smoking or environmental factors, as the incidence of lung cancer, is not proportionately increasing. CONCLUSION: The old concept that Schistosomiasis is associated with SCC should be revaluated as most cases are associated with TCC. Relying on the histopathology for confirmation of Schistosomiasis in our research studies appears to be non-accurate and leads to irrelevant results.

show abstract

Section: Introductionmentioning

confidence: 99%