Bladder overactivity and post-void residual: Which relates more to systemic atherosclerotic markers?

Abstract

Several studies have shown relationship between the lower urinary tract dysfunction (LUTD) and atherosclerosis. However, no study is available to see which LUTD relates more to atherosclerosis, among detrusor overactivity and post-void residual. In order to answer this question, we present data of urodynamic and atherosclerosis tests. Methods: We performed standard urodynamics and two atherosclerosis tests, i.e., a cardio-ankle vascular stiffness index (CAVI) test and a duplex carotid ultrasonography. Patients: We have 183 patients; 109 men (mean age 66.3 years), 74 women (mean age 66.4 years); all age > 60 years. Results: Detrusor overactivity is related with high CAVI value (p < 0.05) but not with carotid intima-media thickness. Post-void residuals did not show such relation. Conclusion: Urodynamic LUTD, particularly detrusor overactivity that may indicate central etiology is positively related with systemic atherosclerosis as measured by CAVI. Post-void residuals that may indicate peripheral etiology did not show such relation.

Diabetic Cystopathy Occurs Independently from Other Atherosclerotic Risks

“…The test methods for determining LUTD (using equipment from Urovision and Life-Tech Inc., Houston, TX, USA) were according to the International Continence Society standards. They included ultrasound echography of the prostate gland in all men (men with a prostate volume > 20 mL were excluded), a nerve conduction study (Neuropack M2; Nihon Kohden Inc., Tokyo, Japan), a cardio-ankle vascular stiffness index test [6] (pulse wave velocity-derived parameter) using a VaSera instrument (Fukuda Denshi Inc., Tokyo, Japan), and an ultrasound Doppler echography (SSA-260A; Toshiba, Inc, Tokyo, Japan). Data were analyzed by Student’s t test and Mann-Whitney U test.…”

Possible Clinical Benefits of Cardio-Ankle Vascular Index Measurement in Urological Diseases

“…Furthermore, there was no significant difference in vascular function between the patients with a large post-void residual volume and the control The authors suggested that a large post-void residual volume might be associated with local factors, and the autonomic dysfunction of the bladder might be related to systemic vascular pathologies. 38 Increased arterial stiffness may affect tissue healing by causing vascular dysfunction. Koguchi et al cross-sectionally examined OAB symptoms in patients who underwent robot-assisted laparoscopic radical prostatectomy for prostate cancer.…”

Family Physician’s Educational Interview with Patients Helps in Early Recognition of Lower Urinary Tract Symptoms

“…2 Furthermore, LUTS should be recognized and treated as early as possible. Although symptoms manifest in the context of LUT, LUTS can be a sign of serious medical conditions with an etiology in other organic systems, [3][4][5][6][7][8][9][10] or it can serve as base for the development of other diseases, [11][12][13][14] and it significantly decreases the quality of life. [15][16][17][18] However, primary health care, and especially patients, still do not recognize LUTS early enough.…”