Bladder teratoma in a maned wolf (<i>Chrysocyon brachyurus</i>)

Abstract

Background: Teratomas are germ cell tumors, comprised of a mixture of tissue types and with tissue foreign to their site of origin. Case Description: A 5.5-year-old intact female maned wolf (Chrysocyon brachyurus) was treated for recurrent stranguria and suspected cystitis. Due to lack of resolution, the wolf was anesthetized for further evaluation. The urinary bladder was firm on palpation, with a markedly thickened wall and no observable lumen on ultrasound. Neoplastic infiltration was suspected on double contrast cystogram and confirmed via surgical exploration. The lesion was inoperable and the wolf was euthanized. Gross necropsy revealed two poorly distinguished masses infiltrating the urinary bladder dorsally and caudoventrally, with minimal remaining lumen. Histopathologic examination of the bladder and associated masses revealed a neoplasm comprised of multiple tissue types. Vascular invasion was noted. Conclusion:The neoplasm was diagnosed as an extragonadal teratoma. Few extragonadal teratomas have been described and this is the first report of a teratoma originating in the urinary bladder of a non-human species.

Rescue and rehabilitation of maned wolf (Chrysocyon brachyurus) in Paraguay: Case description

“…(2013) in the ultrasound evaluations performed on five adult individuals, where they also refer to the difficulty in visualising the non‐gravid uterus. Another work reports a bladder teratoma found through ultrasound evaluation (Fox et al., 2019).…”

“…The measurements obtained in the present case with regard to the thickness of the stomach walls (Figure 5) and the average thickness of the intestines, as well as the contents of the gall bladder (Figure 4), match the measurements reported by Guimarães et al (2013) in the ultrasound evaluations performed on five adult individuals, where they also refer to the difficulty in visualising the non-gravid uterus. Another work reports a bladder teratoma found through ultrasound evaluation (Fox et al, 2019).…”

Dentigerous Equine Teratoma in a Stallion: Surgical Management and Clinicopathology

“…Furthermore, it has been demonstrated that most of these neoplasms derive from anomalies in the ectodermal layer and in a minority from the endodermal layer. Teratomas can be classified as mature and immature based on cell differentiation, therefore they can consist of different mature and immature tissues derived from the three layers of germ cells [ 9 ]. Testicular cancer accounts for only 1% of malignant tumors in both humans and animals [ 10 ].…”

Comparison of immunohistochemical profiles of ovarian germ cells in dysgerminomas of a captive maned wolf and domestic dogs

“…12 The species is listed as near-threatened by the IUCN. 11 Information regarding neoplastic diseases in maned wolves is scarce and mainly restricted to a few case reports, such as mammary tumors, 6 pancreatic gastrinoma, 5 bladder teratoma, 8 and ovarian tumors. 2,15 Dysgerminoma is among the most common ovarian tumor in this species, and this high prevalence is suspected to be the result of a hereditary predisposition.…”