2022
DOI: 10.31083/j.rcm2308286
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Bleeding Complications in Patients Undergoing Percutaneous Coronary Intervention

Abstract: Percutaneous coronary intervention (PCI) is considered a relatively safe procedure associated with low rates of complications, but is inevitably associated with short and mid-to-long term increased bleeding risk. Besides the short term risk associated with the arterial access to perform PCI, enhanced bleeding risk persists for several months, given the need for antithrombotic therapy to prevent procedurerelated thrombotic complications as well as ischemic recurrences. Bleeding is a powerful harbinger of advers… Show more

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Cited by 22 publications
(14 citation statements)
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“…Conversely, from the past decade, a particular attention has been paid to the most relevant adverse event associated with antithrombotic therapy: bleeding (9,14). Indeed, with the advent of second and third generation DES, the incidence of ST, including those occurring late and very late after PCI, has dramatically reduced, making prolonged and intense antithrombotic therapies no longer necessary for this purpose (13).…”
Section: De-escalation: Why?mentioning
confidence: 99%
See 3 more Smart Citations
“…Conversely, from the past decade, a particular attention has been paid to the most relevant adverse event associated with antithrombotic therapy: bleeding (9,14). Indeed, with the advent of second and third generation DES, the incidence of ST, including those occurring late and very late after PCI, has dramatically reduced, making prolonged and intense antithrombotic therapies no longer necessary for this purpose (13).…”
Section: De-escalation: Why?mentioning
confidence: 99%
“…In particular, a more prolonged and intense antithrombotic therapy has been implemented in the attempt of preventing ST, a much feared complication of PCI associated with poor prognosis, whose incidence was relatively more frequent with the advent of first generation drug eluting stent (DES) ( 13 ). Conversely, from the past decade, a particular attention has been paid to the most relevant adverse event associated with antithrombotic therapy: bleeding ( 9 , 14 ). Indeed, with the advent of second and third generation DES, the incidence of ST, including those occurring late and very late after PCI, has dramatically reduced, making prolonged and intense antithrombotic therapies no longer necessary for this purpose ( 13 ).…”
Section: De-escalation: Why?mentioning
confidence: 99%
See 2 more Smart Citations
“…Bleeding events have a significant downstream impact on mortality and morbidity outcomes among patients undergoing PCI ( 82 ). Sex-related differences have been observed also in terms of bleeding risk.…”
Section: Introductionmentioning
confidence: 99%