Bleeding disorders seen in the dental practice

Abstract

Dentists may encounter patients with various types of bleeding disorders in their daily practice. Initial recognition of such bleeding disorders and their possible systemic causes, as well as knowing when to refer those cases to secondary care, plays a crucial and important role in reducing potential complications and negative side-effects. This article will give an account of the most common bleeding disorders that dentists might find in their daily dental practice. This will be followed by another article that will cover the management of congenital and acquired disorders found in the dental practice.

Hemofilias e Doença de von Willebrand: uma revisão de literatura

“…O FvW é uma glicoproteína produzida pelas células endoteliais e megacariócitos, presente no plasma e nas plaquetas. Ele tem duas funções principais: (1) de formar a ponte que permite a aderência das plaquetas na superfície endotelial danificada, promovendo a formação do tampão plaquetário no local da lesão endotelial e (2) a de ligar e transportar o fator VIII (FVIII), protegendo-o da degradação proteolítica no plasma tornando-o mais estável 4,3,17 .…”

“…Ele geralmente é confirmado com a combinação de anormalidades de plaquetas testes de função uma diminuição no fator von Willebrand, assim como também a diminuição proporcional da atividade do fator VIII. O tipo II, por sua vez, tem quatro subtipos (A, B, M, N), todos os quais são defeitos qualitativos e geralmente todos são dominantes autossômicos e o tipo III é raro, mas muito grave, caracterizado pela herança autossômica recessiva e assemelha-se, geralmente, a hemofilia A 4,16,17 .…”

Management of Odontogenic Buccal Space Infection in Patient with Severe Hemophilia A - Case Report

“…The usual protocol for the management of patients having odontogenic space infection is incision and drainage, removal of the focus and antibiotic along with supportive measures. However, when treating patients with bleeding disorders such as hemophilia, the clinician must pay special attention to treatment planning and consultation with the patient's hematologist as well his physician [3]. These patients may require prophylactic factor VIII infusion prior to any surgical procedure, various adjustments to their treatment perioperative, and special precautions postoperatively.…”