Bleomycin-induced pulmonary nodules: A variant of bleomycin pulmonary toxicity

Zucker, Peter K.; Khouri, Nagi F.; Rosenshein, Neil B.

doi:10.1016/0090-8258(87)90174-0

Cited by 17 publications

(4 citation statements)

References 11 publications

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“…Paraquat ingestion usually results in diffuse alveolar damage, but hyaline membranes were not present in a fatal case with intra-alveolar fibrosis [310]. Organising pneumonia has been Amiodarone [90,230,[233][234][235][236][237][238][239][240] Amphotericin B [241] Bleomycin [18,[242][243][244][245][246][247][248][249][250][251][252] Busulfan [230,253,254] Busulfan and cyclophosphamide [230] Carbamazepine [255,256]; in association with carbamazepine induced lupus [257] Cephalosporin (cefradin) [258] Chlorambucil [259] Doxorubicin Possible recall after radiation to the breast [260] Fluvastatin [261] Gold salts [262,263] Hexamethonium [264] Interferon-a [264,265] Interferon-a2b, pegylated interferon a2b [266] Interferon-a + cytosine arabinoside [267] Interferon + ribavirin [266] Interferon-b1a [268,…”

Section: Fungimentioning

confidence: 99%

Cryptogenic organising pneumonia

Jf¹

2006

Eur Respir J

484

466

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Organising pneumonia is defined histopathologically by intra-alveolar buds of granulation tissue, consisting of intermixed myofibroblasts and connective tissue. Although nonspecific, this histopathological pattern, together with characteristic clinical and imaging features, defines cryptogenic organising pneumonia when no cause or peculiar underlying context is found. Rapid clinical and imaging improvement is obtained with corticosteroid treatment, but relapses are common after stopping treatment.

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Section: Fungimentioning

confidence: 99%

Cryptogenic organising pneumonia

Jf¹

2006

Eur Respir J

484

466

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“…[63][64][65][66][67] At histology, these nodules disclose an OP pattern or other inflammatory features but no tumor cells, and they disappear under corticosteroid treatment or even spontaneously. 63,65 Another example is provided by occurrence of OP in women having received radiation therapy for breast cancer. This syndrome has been first described in 1995, 68,69 and numerous reports have since then confirmed these initial observations.…”

Section: Distinction Between Secondary Op and Copmentioning

confidence: 97%

Cryptogenic Organizing Pneumonia

Lazor¹,

Cordier²

2005

Clinical Pulmonary Medicine

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“…CT imaging may often show pulmonary nodules predominantly localized in the sub-pleural region of the lower third of lungs. Such lesions can mimic, should be carefully monitored, and should never be treated as metastases ( 32 ).…”

Section: The Role Of Computed Tomography and Magnetic Resonance In DImentioning

confidence: 99%

Intricacies of Radiographic Assessment in Testicular Germ Cell Tumors

Makovnik

Rejleková

Uhrin³

et al. 2021

Front. Oncol.

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Testicular germ cell tumors (GCTs) are malignancies with a unique biology, pathology, clinical appearance, and excellent outcomes. A correct radiographic assessment of GCTs is extremely important for the clinical management in several typical scenarios. Advancements in the field of diagnostic medicine bring an increasing number of sophisticated imaging methods to increase the performance of imaging studies. The conventional computed tomography (CT) remains the mainstay of diagnostic imaging in the management of GCTs. While certain improvements in the sensitivity and specificity are suggested with magnetic resonance (MR) imaging with lymphotrophic nanoparticles in evaluating retroperitoneal lymph nodes during the staging procedure, further exploration in larger prospective studies is needed. A common diagnostic dilemma is assessing the post-chemotherapy residual disease in GCTs. Several studies have consistently shown advantages in the utility of positron emission tomography (PET) scanning in post-chemotherapy residual retroperitoneal lymph nodes in patients with seminoma, but not with non-seminoma. Recommendations suggest that seminoma patients with a residual disease in the retroperitoneum larger than 3 cm should be subjected for PET scanning with 18-fluorodeoxyglucose. Relatively high sensitivity, specificity and a negative predictive value (80–95%) may guide clinical decision to spare these patients of high morbidity of an unnecessary surgery. However, a positive predictive value of around 50% renders PET scanning difficult to interpret in the case of positive finding. These patients often require extremely difficult surgical procedures with the high risk of post-operative morbidity. Therefore, seminoma patients with PET positive residual masses larger than 3 cm still remain a serious challenge in the decision making of nuclear medicine specialist, oncologists, and urologic surgeons. In this article, we aim to summarize data on controversial dilemmas in staging procedures, active surveillance, and post-chemotherapy assessment of GCTs based on the available published literature.

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Bleomycin-induced pulmonary nodules: A variant of bleomycin pulmonary toxicity

Cited by 17 publications

References 11 publications

Cryptogenic organising pneumonia

Cryptogenic organising pneumonia

Cryptogenic Organizing Pneumonia

Intricacies of Radiographic Assessment in Testicular Germ Cell Tumors

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