Blepharospasm: an uncommon adverse effect caused by long-term administration of olanzapine

Arora, Tarun; Maharshi, Vikas; Rehan, Harmeet Singh; Nagar, Pravesh

doi:10.1515/jbcpp-2016-0037

Cited by 9 publications

(3 citation statements)

References 8 publications

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“…As highlighted in this case, quetiapine was initiated and eventually led to the resolution of the blepharospasm. A similar case of olanzapine-induced tardive blepharospasm was reported and a complete recovery of symptoms was achieved by stopping the offending drug and switching to quetiapine (17).…”

mentioning

confidence: 72%

“…Tardive blepharospasm, which is a recognized subtype of TD has rarely reported (17). The pathophysiology of tardive blepharospasm is still unknown.…”

Section: Discussionmentioning

confidence: 99%

“…The data on the prevalence of tardive blepharospasm associated with a specific antipsychotic treatment is still limited. Several cases of olanzapine-induced blepharospasm have reported (17).…”

Section: Discussionmentioning

confidence: 99%

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Olanzapine-Induced Tardive Blepharospasm: A Case Report

Poh

Wahab

Theng

et al. 2019

Iran J Psychiatry Behav Sci

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Introduction: The objective of this case report was to highlight one of the uncommon subtypes of tardive dyskinesia (TD) as tardive blepharospasm secondary to olanzapine. Case Presentation: We reported a rare case of young-onset schizophrenia in an adolescent patient, who was treated with olanzapine, but subsequently developed tardive blepharospasm. Clinical resolution of the blepharospasm after olanzapine was stopped and switched to quetiapine. Conclusions: Tardive blepharospasm can be a regarded as a presentation of tardive dyskinesia. Complete recovery of the symptoms can be achieved by stopping the offending drug early and switching to a serotonin-dopamine receptor antagonist.

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mentioning

confidence: 72%

“…Tardive blepharospasm, which is a recognized subtype of TD has rarely reported (17). The pathophysiology of tardive blepharospasm is still unknown.…”

Section: Discussionmentioning

confidence: 99%