Block Copolymers From Living Emulsion Polymerization: Reactor Operating Strategies and Blocking Efficiency

Altarawneh, Ibrahem; Gomes, Vincent G.; Srour, M.H.

doi:10.1002/mren.201100052

Cited by 3 publications

(1 citation statement)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A* [103,493] (St) [510,511] (BA) [112] (BA) [511] (MA) [511] NIPAm [112] VAc [512] VPv [513] NVC [514] NVP [103,493,515] NVP [513] NVPip [516] NVC [514,515] VAc/VPv [513] (BA-b-St) [511] (MA-b-St) [511] BA-b-NIPAm [112] NVC-b-Ac [514] NVP-b-NVC [515] NVPip-b-VAc [516] NVC-b-NVP [515] NVC-b-VAc [514] (NIPAm/NVPI) [517] (Continued ) [512] (VAc) [512] (230) [512] (230-b-VAc) [512] 231…”

Section: O S S Cnmentioning

confidence: 99%

Living Radical Polymerization by the RAFT Process – A Third Update

2012

View full text Add to dashboard Cite

This paper provides a third update to the review of reversible deactivation radical polymerization (RDRP) achieved with thiocarbonylthio compounds (ZC(¼S)SR) by a mechanism of reversible addition-fragmentation chain transfer ( Chem. 2009Chem. , 62, 1402. This review cites over 700 publications that appeared during the period mid 2009 to early 2012 covering various aspects of RAFT polymerization which include reagent synthesis and properties, kinetics and mechanism of polymerization, novel polymer syntheses, and a diverse range of applications. This period has witnessed further significant developments, particularly in the areas of novel RAFT agents, techniques for end-group transformation, the production of micro/nanoparticles and modified surfaces, and biopolymer conjugates both for therapeutic and diagnostic applications.

show abstract

Section: O S S Cnmentioning

confidence: 99%

Living Radical Polymerization by the RAFT Process – A Third Update

2012

View full text Add to dashboard Cite

show abstract

Hydrophobic Polystyrene‐Modified Gelatin Enhances Fast Hemostasis and Tissue Regeneration in Traumatic Brain Injury

Liu

et al. 2023

Adv Healthcare Materials

View full text Add to dashboard Cite

Hemostatic sealant is required to deal with blood loss, especially in the scenario of traumatic brain injury (TBI), which presents high rates of morbidity and disability. Hemostasis in surgery with traditional gelatin‐based sealants often leads to blood loss and other issues in brain because of the hydrophilic gelatin swelling. Herein, hydrophobic effects on the hemostasis in TBI surgery are studied by tuning the chain length of polystyrene (PS) onto methylacrylated gelatin (Gel‐MA). The hydrophobicity and hemostatic efficiency can be tuned by controlling the length of PS groups. The platelet activation of modified sealants Gel‐MA‐2P, Gel‐MA‐P, and Gel‐MA‐0.5P is as much as 17.5, 9.1, and 2.1 times higher than Gel‐MA in vitro. The hemostatic time of Gel‐MA‐2P, Gel‐MA‐P, and Gel‐MA‐0.5P groups is 2.0‐, 1.6‐, and 1.1‐folds faster than that in Gel‐MA group in TBI mice. Increased formation of fibrins and platelet aggregation can also be observed in vitro by scanning electron microscopy. Animal's mortality is lowered by 46%, neurologic deficiency is reduced by 1.5 times, and brain edema is attenuated by 10%. Protein expression is further investigated to exhibit toxic iron‐related processes caused by delayed hemostasis and activation of platelets via PI3K/PKC‐α signaling. The hydrophobic Gel‐MA has the potential in hemostatic TBI and promotes nervous system recovery in brain with the potentials in clinics.

show abstract

Advantages of Block Copolymer Synthesis by RAFT-Controlled Dispersion Polymerization in Supercritical Carbon Dioxide

et al. 2013

View full text Add to dashboard Cite

Reversible addition–fragmentation chain transfer (RAFT)-controlled block copolymer synthesis using dispersion polymerization in supercritical carbon dioxide (scCO2) shows unprecedented control over blocking efficiency. For PMMA-b-PBzMA and PMMA-b-PSt the blocking efficiency was quantified by measuring homopolymer contaminants using the techniques of GPC deconvolution, gradient polymer elution chromatography (GPEC), and GPC dual RI/UV detection. A new, promising method was also developed which combined GPC deconvolution and GPEC. All techniques showed that blocking efficiency was significantly improved by reducing the radical concentration and target molecular weight. Estimated values agreed well with (and occasionally exceeded) theory for PMMA-b-PBzMA. The heterogeneous process in scCO2 appeared to cause little or no further hindrance to the block copolymerization procedure when reaction conditions were optimized. High blocking efficiencies were achieved (up to 82%) even at high conversion of MMA (>95%) and high molecular weight. These data compare favorably to numerous published reports of heterogeneous syntheses of block copolymers.

show abstract

Block Copolymers From Living Emulsion Polymerization: Reactor Operating Strategies and Blocking Efficiency

Cited by 3 publications

References 22 publications

Living Radical Polymerization by the RAFT Process – A Third Update

Living Radical Polymerization by the RAFT Process – A Third Update

Hydrophobic Polystyrene‐Modified Gelatin Enhances Fast Hemostasis and Tissue Regeneration in Traumatic Brain Injury

Advantages of Block Copolymer Synthesis by RAFT-Controlled Dispersion Polymerization in Supercritical Carbon Dioxide

Contact Info

Product

Resources

About