2020
DOI: 10.11604/pamj.2020.35.55.12622
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Blood donor safety: prevalence and associated factors for cytomegalovirus infection among blood donors in Minna-Nigeria, 2014

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“…Anti-HCMV IgM detection indicates a recent infection, and our study showed that only 1.6% of donors were IgM-positive. Our results fall within the range of 0.4-10% rate reported in other countries, such as Switzerland, Tanzania, and China [ 27 - 29 , 31 ]. Anti-HCMV IgM­ positivity indicates a recent infection (primary, reactivation, or reinfection), and anti-HCMV IgG has been detected in secondary (reactivation) HCMV infections in some HCMV-infected individuals [ 32 ].…”
Section: Discussionsupporting
confidence: 87%
“…Anti-HCMV IgM detection indicates a recent infection, and our study showed that only 1.6% of donors were IgM-positive. Our results fall within the range of 0.4-10% rate reported in other countries, such as Switzerland, Tanzania, and China [ 27 - 29 , 31 ]. Anti-HCMV IgM­ positivity indicates a recent infection (primary, reactivation, or reinfection), and anti-HCMV IgG has been detected in secondary (reactivation) HCMV infections in some HCMV-infected individuals [ 32 ].…”
Section: Discussionsupporting
confidence: 87%
“…Cytomegalovirus is a double-strand DNA enveloped Herpesviruses, highly ubiquitous throughout the world, the prevalence rate inversely correlated with the socioeconomic status of the human population (Firth, 2015), In developing countries the prevalence rate of CMV ranges from 85-100% (Cannon wt al., 2010). Primary infection with HCMV is usually asymptomatic or exhibits infectious mononucleosis-like symptoms in immunocompetent individuals (BAWA, 2014). However, in immunocompromised patients a life-threatening infection may be encountered (Ljungman, 2004).…”
Section: Introductionmentioning
confidence: 99%