Blood donors

Abstract

Evaluation of TTI (transfusion transmitted infections) are essential for assessing the safety of blood supply and monitoring the efficacy of currently employed screening procedures. Objective: To assess the prevalence of HBV, HCV and HIV among replacement donors and voluntary donor in association with the Kuppuswamy’s socioeconomic status. Material and Methods: A retrospective analysis of total 10569 blood donors from Jan2014 to Sep 2015 was conducted at a blood bank in a tertiary care hospital in North India, Teerthanker Mahaveer Medcial college and research centre. Donor with hemoglobin (Hb) less than 12.5gm% or known seropositive for TTI were deferred and excluded from the study group. The hemoglobin level was measured by copper sulphate method, samples were screened for: a) HIV-1 and p antigen ELISA kits from Mitra& Co. ltd , for anti HIV I and II 4th generation Microlisa- HIV Ag and Ab. b) HBsAg- Hepalisac) anti HCV d) Malaria Age) Syphilis. Observation: The prevalence of HBV and HCV was noted to be higher among replacement donors as compared to voluntary donors, while in HIV, the prevalence was noted only in voluntary donors. Total 10,569 blood donors were grouped as per the KSESS, maximum donors in lower middle class III-5789.