Blood pressure variability and the development of early neurological deterioration following acute ischemic stroke

Abstract

BP variability is independently and linearly associated with the development of neurologic deterioration in acute stage of ischemic stroke.

Acute in‐hospital blood pressure variability predicts early neurological deterioration in acute minor stroke or transient ischemic attack with steno‐occlusive arterial disease

“…And, the rate of END was 32.5% in this study, which was consistent with the rates in previous studies . And also, our findings were similar to that in the Chungs' study . Both studies suggested that the acute in‐hospital BPV was strongly associated with the risk of having a END.…”

“…Studies had demonstrated that increased BP in the acute stage of ischemic stroke may be associated with poor functional outcome because there is augmentation of cerebral edema, hemorrhagic transformation, or stroke recurrence . In addition, variability of BP in the acute stage of ischemic stroke is also reported to be associated with stroke outcome with respect to mortality, lesion growth on diffusion‐weighted MRI, functional outcome, and symptomatic hemorrhagic transformation . In this study, BPV was proved to be related to the development of END in patients with acute minor stroke or TIA due to steno‐occlusive arterial disease.…”

“…In the field of cardiovascular disease, BPV is becoming increasingly recognized as an important predictor for future cardiovascular events . Recent several studies also tell us that high BPV is not only predictive of stroke but also clinical outcomes following general ischemic stroke . However, to the best of our knowledge, there are limited data on the relationship between BPV and END following acute minor stroke or TIA.…”

Admission systolic blood pressure and outcomes in large vessel occlusion strokes treated with endovascular treatment

“…We did not measure the correlation between clot burden and presenting BP and their impact on the final outcome. Also, we did not assess other components of BP including pulse pressure, mean arterial pressure, and (more specifically) BP variability, which has been associated with early neurological deterioration in patients with AIS 26. Moreover, we did not record serial BP measurements after admission and the variability of BP levels prior to and during EVT, and consequently we were unable to assess the potential impact of periprocedural BP fluctuations on stroke outcome.…”

Neurology Case Studies

“…6 Farooq & Gorelick Blood pressure variability in acute stroke patients with intracranial atherosclerotic occlusive disease may be associated with neurologic deterioration and poor neurologic outcome. 7 Therefore, augmentation of BP and reduction of BP fluctuations in the acute setting may be useful, especially when auto-regulatory mechanisms are compromised in the area of cerebral infarction and the surrounding penumbra. The penumbra may be thought of as a shadow zone of compromised cerebral blood flow or perfusion in which brain tissue is rendered ischemic and dysfunctions, but frank infarction has not occurred.…”