Blood velocity pulse quantification in the human conjunctival pre-capillary arterioles

Wall shear stress quantification in the human conjunctival pre-capillary arterioles in vivo

“…The system produced digital images of 320 × 240 pixels at a frame rate of 96 frames per second (fps) with an enhanced maximum magnification of 242× and a digital resolution of 1.257± 0.004 μm/pixel. More details on the experimental set up can be found elsewhere (Koutsiaris et al, 2010).…”

“…Mobile images were translated along the x and y axes (two-dimensional registration) so that its characteristic regions were aligned with the 'reference' image. The manual registration procedure is described in more detail in a previous work (Koutsiaris et al, 2010).…”

“…The objective of this work was the quantification of blood volume flow (Q), wall shear rate (WSR) and wall shear stress (WSS) in the human smallest diameter arterioles of the eye using axial velocity measurements from a previous work (Koutsiaris et al, 2010).…”

“…The aforementioned method was applied here, for the first time, to the precapillary arterioles of the human eye where significant pulsation exists (Koutsiaris et al, 2010). So, averages of Q, WSR and WSS, during the cardiac cycle, are presented separately from systolic and diastolic values.…”

Comment on ‘Distribution of normal superficial ocular vessels in digital images’

“…I found that in the discussion part of the paper, paragraph 2, many of the older references with qualitative methods had been omitted during multiple editions, but the concept stated in the sentence have not been changed, and the 4 references retained [3][4][5][6], all used quantitative methods of analysis of the conjunctival vessels and not qualitative methods. Hereby I apologize Dr Koutsiaris and the authors of the 3 other manuscripts for this mistake.…”