Bloqueio simpático esquerdo por videotoracoscopia no tratamento da cardiomiopatia dilatada

Pêgo-Fernandes, Paulo Manuel; Moreira, Luíz Felipe Pinho; Souza, Germano Emílio Conceição; Bacal, Fernando; Bocchi, Edimar Alcides; Stolf, Noedir Antônio Groppo; Jatene, Fábio Biscegli

doi:10.1590/s0066-782x2010005000152

Cited by 14 publications

(7 citation statements)

References 21 publications

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“…29 More recently, within our setting, left sympathetic therapeutic block by means of thoracoscopy in patients with heart failure has shown promising results. 12 The clinical improvement and the better left ventricular function observed in patients undergoing this procedure over the first six months of follow-up have been similar to those documented from using other well established procedures for treating chronic heart failure. Findings from imaging examinations using 123I-metaiodobenzylguanidine have indicated that bilateral upper thoracic sympathectomy mildly suppresses the activation of the sympathetic nerve system, like in beta-blocker therapy.…”

Section: -19supporting

confidence: 72%

Surgical treatment of heart failure: a hot topic

Pêgo-Fernandes

Monteiro

2011

Sao Paulo Med. J.

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Section: -19supporting

confidence: 72%

Surgical treatment of heart failure: a hot topic

Pêgo-Fernandes

Monteiro

2011

Sao Paulo Med. J.

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“…The results suggest a difference between the two groups regarding improvement in the functional class. The patients undergoing sympathectomy showed a statistically significant improvement in the six-minute walk test and the quality of life questionnaire (12,13).…”

mentioning

confidence: 95%

Surgical Sympathectomy: Can it be useful in cardiology?

Pêgo-Fernandes¹

2020

Clinics

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“…[ 1 2 ] It has become the primary surgical procedure opted for sympathectomy in primary hyperhidrosis cases through its superiorities. [ 2 3 ]…”

mentioning

confidence: 99%

Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery

Oncel

Kiyici

et al. 2016

Ann Thorac Med

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BACKGROUND:Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-modified albumin (IMA), malondialdehyde (MDA), and nitric oxide (NO) levels in patients with primary hyperhidrosis was aimed.METHODS:Twenty-six patients who underwent videothoracoscopic surgery were contributed in this study. Venous blood samples were obtained from these patients 1 h before and after the surgery. IMA, MDA, and NO levels were measured in serum samples by colorimetric methods. Albumin concentrations were also measured for each sample, and albumin-adjusted IMA levels were calculated.RESULTS:Postoperative IMA, albumin-adjusted IMA, and MDA values were significantly higher compared to the preoperative values (P = 0.003, 0.027, 0.018, respectively). However, postoperative NO levels were lower than the preoperative values (P = 0.002). There was no significant difference between pre- and postoperative albumin concentrations, and there was no significant correlation between the parameters tested.CONCLUSIONS:We can conclude that elevation in MDA and IMA levels after videothoracoscopic surgery was caused by increased oxidative stress due to minimal ischemia-reperfusion injury after the infusion of CO2 during the surgical process. Videothoracoscopic sympathectomy operation causes a decrease in NO production, and this should be taken in consideration when evaluating nitrosative stress in videothoracoscopic surgery.

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Bloqueio simpático esquerdo por videotoracoscopia no tratamento da cardiomiopatia dilatada

Abstract: Background: The level of sympathetic nervous activity is a major determinant of prognosis in patients with heart failure.

Cited by 14 publications

References 21 publications

Surgical treatment of heart failure: a hot topic

Surgical treatment of heart failure: a hot topic

Surgical Sympathectomy: Can it be useful in cardiology?

Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery

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