Blu-ray DVD as SERS substrate for reliable detection of albumin, creatinine and urea in urine

Chamuah, Nabadweep; Saikia, Ankita; Joseph, Aneesh M.; Nath, Pabitra

doi:10.1016/j.snb.2019.01.031

Cited by 45 publications

(36 citation statements)

References 41 publications

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“…The IR and Raman spectroscopy have advantage of easy preparation of samples to analyze. They require no specific reagents, or no reagents at all, no preconcentration or dilution, as evidenced from [ 158 , 162 , 165 ]. They are rapid.…”

Section: Discussionmentioning

confidence: 99%

“…Chamuah et al used a blu-ray DVD as a SERS substrate for the detection of albumin, creatinine, and urea in urine [ 165 ]. The minimum concentration of albumin, creatinine, and urea which can be measured by Raman spectrometer is 0.1 mg/L, 0.2 mg/L, and 0.6 mg/L respectively.…”

Section: Detection Techniquesmentioning

confidence: 99%

“…Chamuah et al assigned the signature Raman peaks to the corresponding vibrations in analytes [ 165 ]: for albumin – peaks at 1208 cm −1 and 1370 cm −1 are attributed to SO 2 symmetric stretch and CH bond deformation of albumin. for creatinine – the Raman signature peaks are observed at 888 cm −1 , 958 cm -1 , and 1444 cm- 1 which could be due to C=O stretching, C-C stretching and CH3 anisometric deformation respectively.…”

Section: Detection Techniquesmentioning

confidence: 99%

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Review: Detection and quantification of proteins in human urine

Aitekenov

Gaipov

Bukasov

2021

Talanta

125

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Extensive medical research showed that patients, with high protein concentration in urine, have various kinds of kidney diseases, referred to as proteinuria. Urinary protein biomarkers are useful for diagnosis of many health conditions – kidney and cardio vascular diseases, cancers, diabetes, infections. This review focuses on the instrumental quantification (electrophoresis, chromatography, immunoassays, mass spectrometry, fluorescence spectroscopy, the infrared spectroscopy, and Raman spectroscopy) of proteins (the most of all albumin) in human urine matrix. Different techniques provide unique information on what constituents of the urine are. Due to complex nature of urine, a separation step by electrophoresis or chromatography are often used for proteomics study of urine. Mass spectrometry is a powerful tool for the discovery and the analysis of biomarkers in urine, however, costs of the analysis are high, especially for quantitative analysis. Immunoassays, which often come with fluorescence detection, are major qualitative and quantitative tools in clinical analysis. While Infrared and Raman spectroscopies do not give extensive information about urine, they could become important tools for the routine clinical diagnostics of kidney problems, due to rapidness and low-cost. Thus, it is important to review all the applicable techniques and methods related to urine analysis. In this review, a brief overview of each technique’s principle is introduced. Where applicable, research papers about protein determination in urine are summarized with the main figures of merits, such as the limit of detection, the detectable range, recovery and accuracy, when available.

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Section: Discussionmentioning

confidence: 99%

Section: Detection Techniquesmentioning

confidence: 99%

Section: Detection Techniquesmentioning

confidence: 99%

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Review: Detection and quantification of proteins in human urine

Aitekenov

Gaipov

Bukasov

2021

Talanta

125

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“…The following is an outline of the other techniques in which MNPs, especially AuNPs, have been used for creatinine detection: dynamic light scattering (DLS) and surface-enhanced Raman spectroscopy (SERS). 39,40 A sensitive and selective approach for creatinine detection using calix [4]arene-functionalized AuNPs detected by DLS has been developed. 39 The fast response of this material to creatinine is attributed to hydrogen bonding and the electrostatic interaction between the amine group of creatinine and the calix [4]arene compound, which can be used to quantify the creatinine concentration.…”

Section: •1•3 Principle Of Colorimetric Methods For Creatinine Detection Based On Aunps and Agnpsmentioning

confidence: 99%

Colorimetric Detection Based on Localized Surface Plasmon Resonance for Determination of Chemicals in Urine

et al. 2020

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Colorimetric sensors based on localized surface plasmon resonance (LSPR) have attracted much attention for biosensor and chemical sensor applications. The unique optical effect of LSPR is based on the nanostructure of noble metals (e.g., Au, Ag, and Al) and the refractive index of the environment surrounding these metal nanomaterials. When either the structure or the environment of these nanomaterials is changed, their optical properties change and can be observed by spectroscopic techniques or the naked eye. Colorimetric-probe-based LSPR provides a simple, rapid, real-time, nonlabelled, sensitive biochemical detection and can be used for point-of-care testing as well as rapid screening for the diagnosis of various diseases. Gold and silver nanoparticles, which are the two most widely used plasmonic nanomaterials, demonstrate strong and sensitive LSPR signals that can be used for the selective detection of several chemicals in biochemical compounds provided by the human body (e.g., urine and blood). This information can be used for the diagnosis of several human health conditions. This paper provides information regarding colorimetric probes based on LSPR for the detection of three major chemicals in human urine: creatinine, albumin, and glucose. In addition, the mechanisms of selective detection and quantitative analysis of these chemicals using metal nanoparticles are discussed along with colorimetric-detection-based LSPR for many other specific chemicals that can be detected in urine, such as catecholamine neurotransmitters, thymine, and various medicines. Furthermore, issues regarding the use of portable platforms for health monitoring with colorimetric detection based on LSPR are discussed.

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“…Chen et al 23 showed the SERS detection of CRN in water with colloidal Ag NPs with a detection limit of 10 mg dL À1 . Nanostructured SERS substrates such as Ag-coated parylene, 24 Jaffe complex-Ag film, 16 nanoporous Au disk, 25 boron nitride/Au nanocomposites, 26 superhydrophobic Ag film, 27 and Au NPdeposited blu-ray DVD 28 were then developed, aiming to improve the sensitivity and signal reproducibility for CRN sensing. However, the fabrication of substrates is timeconsuming and often involves complicated procedures.…”

Section: Introductionmentioning

confidence: 99%