Blue LED as a new treatment to vaginal stenosis due pelvic radiotherapy: Two case reports

Abstract

BACKGROUND Currently, the advancement cancer treatment technology improves overall survival, however, adverse events are still a challenge for health professional. Genitourinary syndrome of menopause and vaginal stenosis are conditions that impact the quality of life of patients undergoing radiotherapy. We present two such cases in patients with previous cervical and endometrial cancer. These conditions were handled with an innovative method using an energy-based device with blue light emitting diode for concomitant vaginal and vulvar irradiation. Positive impact in clinical findings, cytologic changes, and referred symptoms were documented. CASE SUMMARY One patient diagnosed with vaginal severe vaginal stenosis with previous cervix cancer treatment and other patient diagnosed with mild stenosis with severe dyspareunia and recent endometrium cancer treatment were considered for vulvovaginal treatment with weekly blue led device and closely evaluated with repeated validated questionnaires and cytological samples. CONCLUSION This innovative technique showed an improvement in all areas of the examiner's criteria, the cytological criteria, and most bothered symptoms.

Anion-Exchange Blue Perovskite Quantum Dots for Efficient Light-Emitting Devices

“…Recently, blue LEDs have been gradually developed and are widely used in various fields such as agricultural growth [1][2][3][4][5], white LED development [6,7] and biomedical research [8][9][10][11]. The increasingly prevalent medical aesthetic industry has also invested in the study of blue LEDs for teeth whitening and dental care treatment via photodynamic therapy [12], which enables a high-intensity blue light to inhibit the growth of dental plaque and germs on the material surface [13].…”