Blue light-emitting diode light at 405 and 465 nm can inhibit a Miamiensis avidus infection in olive flounder, Paralichthys olivaceus

Roh, Heyong Jin; Kim, Ahran; Kang, Gyoung Sik; Kim, Bo Seong; Kim, Do-Hyung

doi:10.1016/j.aquaculture.2018.04.045

Cited by 15 publications

(13 citation statements)

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“…These toxic species cause widespread oxidative damage to the pathogens, which ultimately leads to death of pathogens (16)(17)(18). This decontamination method has efficacy against a wide range of pathogenic organisms including vegetative bacteria, spore forming bacteria and fungi (17,19,20), with recent studies also demonstrating the potential for inactivation of viruses, protozoa, and parasites (21)(22)(23). Additionally, 405 nm light is safer than UV light wavelengths, with antimicrobial efficacy capable of being achieved at levels that are compatible with mammalian cells (16,(24)(25)(26)(27)(28).…”

Section: Introductionmentioning

confidence: 99%

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

et al. 2020

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Bacterial contamination of ex vivo stored platelets is a cause of transfusion-transmitted infection. Violet-blue 405 nm light has recently demonstrated efficacy in reducing the bacterial burden in blood plasma, and its operational benefits such as non-ionizing nature, penetrability, and non-requirement for photosensitizing agents, provide a unique opportunity to develop this treatment for in situ treatment of ex vivo stored platelets as a tool for bacterial reduction. Sealed bags of platelet concentrates, seeded with low-level Staphylococcus aureus contamination, were 405 nm light-treated (3-10 mWcm −2 ) up to 8 h. Antimicrobial efficacy and dose efficiency was evaluated by quantification of the post-treatment surviving bacterial contamination levels. Platelets treated with 10 mWcm −2 for 8 h were further evaluated for survival and recovery in severe combined immunodeficient (SCID) mice. Significant inactivation of bacteria in platelet concentrates was achieved using all irradiance levels, with 99.6-100% inactivation achieved by 8 h (P < 0.05). Analysis of applied dose demonstrated that lower irradiance levels generally resulted in significant decontamination at lower doses: 180 Jcm −2 /10 mWcm −2 (P = 0.008) compared to 43.2 Jcm −2 /3 mWcm −2 (P = 0.002). Additionally, the recovery of light-treated platelets, compared to non-treated platelets, in the murine model showed no significant differences (P = >0.05). This report paves the way for further comprehensive studies to test 405 nm light treatment as a bactericidal technology for stored platelets.

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Section: Introductionmentioning

confidence: 99%

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

et al. 2020

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“…Translocating phosphatidylserine, which can be detected by Annexin V staining, is important evidence of early apoptosis. Hence, Anx V − /PI − , Anx V + /PI − , and Anx V + /PI + cells have been considered live, early apoptotic, and late apoptotic cells, respectively [21,65]. In this study, although there were no significant differences between the control group and groups treated with 0.2, 1, and 2 mg/mL OxLDL until 8 hpi, the cell distribution in the OxLDL-treated group at 24 and 48 hpi was different from that of the control group.…”

Section: Discussionmentioning

confidence: 99%

“…The liver and head kidney were fixed in 10% neutral-buffered formalin (BBC Biochemical, Mt Vernon, WA, USA), following a previous method [21]. The tissue sections of the liver and kidney were stained with hematoxylin and eosin (H & E) (BBC Biochemical, USA).…”

Section: Histological Analysismentioning

confidence: 99%

Overfeeding-Induced Obesity Could Cause Potential Immuno-Physiological Disorders in Rainbow Trout (Oncorhynchus mykiss)

Roh

Park

Kim

et al. 2020

Animals

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Although over-nutrition from overfeeding-induced obesity is known to be highly associated with metabolic and immunological disorders in humans, little is known about overfeeding-induced obesity in fish farming. The purpose of this study was to investigate changes in immuno-physiological parameters, to better understand the potential risk of overfeeding–induced obesity in fish. Commercial feed was provided to fish in the overfed group until they refuse to eat, but fish in the control group was fed with the feed at 1% bodyweight per day. The hemato-serological, histological, and immunological changes were observed at weeks 2 and 8. Rainbow trout leukocytes were co-incubated with oxidized low-density lipoprotein (OxLDL), and the phagocytes engulfing the OxLDL and the presence of apoptotic cells were evaluated. The body weight, body mass index (BMI), and hepatosomatic index (HSI) index were significantly higher in the overfed group, and high lipid accumulation and fatty changes were also observed in their livers, indicating that the feeding regime used in this study led to overfeeding-induced obesity. Likewise, much higher numbers of and larger vacuoles were observed in overfed fish macrophages, showing unclear boundaries between the cytoplasm and extracellular space. In the overfed group, the expression of IL-10, HSP70, TLR2, and CD36 was significantly higher, and lymphocyte apoptosis was more evident, indicating that overfeeding-induced obese fish might have immunologic disorders. This was the first study to demonstrate that overfeeding-induced obesity could cause an immune-physiological imbalance in rainbow trout, making them more vulnerable to infectious diseases and various stressful conditions. This study will contribute to improvements in fish nutrition, feeding practices, fish nutrition, and disease prevention in the aquaculture industry.

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“…Blue LEDs have the potential to kill unwanted pathogens in aquaculture plants. For example, LED light at 405 and 465 nm were efficient in Olive Flounder ( Paralichthys olivaceus ) and Carp ( Cyprinus carpio ) culture farms to eliminate Miamiensis avidus and Edwardsiella piscicida respectively ( Roh et al, 2018 ). However, at 405 nm the dorsal part of the retina was damaged after 14 days in P. olivaceus , outlining the possibility that these treatments might have deleterious side effects on the fish itself.…”

Section: Impact Of Alan and Leds On Living Organismsmentioning

confidence: 99%

Exposure to Artificial Light at Night and the Consequences for Flora, Fauna, and Ecosystems

et al. 2020

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The present review draws together wide-ranging studies performed over the last decades that catalogue the effects of artificial-light-at-night (ALAN) upon living species and their environment. We provide an overview of the tremendous variety of light-detection strategies which have evolved in living organisms - unicellular, plants and animals, covering chloroplasts (plants), and the plethora of ocular and extra-ocular organs (animals). We describe the visual pigments which permit photo-detection, paying attention to their spectral characteristics, which extend from the ultraviolet into infrared. We discuss how organisms use light information in a way crucial for their development, growth and survival: phototropism, phototaxis, photoperiodism, and synchronization of circadian clocks. These aspects are treated in depth, as their perturbation underlies much of the disruptive effects of ALAN. The review goes into detail on circadian networks in living organisms, since these fundamental features are of critical importance in regulating the interface between environment and body. Especially, hormonal synthesis and secretion are often under circadian and circannual control, hence perturbation of the clock will lead to hormonal imbalance. The review addresses how the ubiquitous introduction of light-emitting diode technology may exacerbate, or in some cases reduce, the generalized ever-increasing light pollution. Numerous examples are given of how widespread exposure to ALAN is perturbing many aspects of plant and animal behaviour and survival: foraging, orientation, migration, seasonal reproduction, colonization and more. We examine the potential problems at the level of individual species and populations and extend the debate to the consequences for ecosystems. We stress, through a few examples, the synergistic harmful effects resulting from the impacts of ALAN combined with other anthropogenic pressures, which often impact the neuroendocrine loops in vertebrates. The article concludes by debating how these anthropogenic changes could be mitigated by more reasonable use of available technology – for example by restricting illumination to more essential areas and hours, directing lighting to avoid wasteful radiation and selecting spectral emissions, to reduce impact on circadian clocks. We end by discussing how society should take into account the potentially major consequences that ALAN has on the natural world and the repercussions for ongoing human health and welfare.

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Blue light-emitting diode light at 405 and 465 nm can inhibit a Miamiensis avidus infection in olive flounder, Paralichthys olivaceus

Cited by 15 publications

References 69 publications

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Overfeeding-Induced Obesity Could Cause Potential Immuno-Physiological Disorders in Rainbow Trout (Oncorhynchus mykiss)

Exposure to Artificial Light at Night and the Consequences for Flora, Fauna, and Ecosystems

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Blue light-emitting diode light at 405 and 465 nm can inhibit a Miamiensis avidus infection in olive flounder, Paralichthys olivaceus

Cited by 15 publications

References 69 publications

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Overfeeding-Induced Obesity Could Cause Potential Immuno-Physiological Disorders in Rainbow Trout (Oncorhynchus mykiss)

Exposure to Artificial Light at Night and the Consequences for Flora, Fauna, and Ecosystems

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Blue light-emitting diode light at 405 and 465 nm can inhibit a Miamiensis avidus infection in olive flounder, Paralichthys olivaceus