Blueberry and cranberry extracts mitigate CCL4-induced liver damage, suppressing liver fibrosis, inflammation and oxidative stress

The Role of Natural Extracts in the Management of Infantile Hemangiomas and Vascular Tumors

“… 49 Molecular mechanisms include inhibition of pro-inflammatory molecule production, inhibition of oxidative stress and products of this process such as DNA damage, inhibition of cancer cell proliferation, and increased apoptosis. 50 , 51 The ingestion of fruits and plant extracts rich in polyphenolic compounds has neuroprotective effects and other positive effects on urinary, gastrointestinal tract, and cardiovascular system. 49 , 52 , 53 The types of berries, active substances, properties, and food methods are summarized in Table 1 .…”

“…et al, 2008 46 Gordillo GM et al, 2021 12 Biswas A et al, 2017 13 Blueberries Vaccinium angustifolium -phenolic compounds -anthocyanins - high antioxidant, anti-inflammatory, antiseptic, anti-tumoral and anti-angiogenic capacity - decrease the activity of multidrug resistance protein-1 - inhibits basal and nonmitochondrial respiration of EOMA cells - Fermented berry juice, jams, compotes, jellies; - Natural berry extract -ethanol–water extract Johnson SA et al, 2013 45 Olsson M.E. et al, 2004 47 Sergazy S et al, 2023 50 Bunea A et al, 2013 51 Black currants Ribes lacustre - phenolic compounds - vitamins C, A, and E - inhibition of pro-inflammatory molecules production, inhibition of oxidative stress, inhibition of cancer cell proliferation and increased apoptosis - neuroprotective effects, positive effects on urinary, gastrointestinal tract and cardiovascular system - aqueous extract from the fruit or leaves - fruits and plant extracts Misikangas M. et al, 2007 48 Kelly E et al, 2017 49 Hossain MZ et al, 2016 52 …”

“…et al, 2008 46 Gordillo GM et al, 2021 12 Biswas A et al, 2017 13 Johnson SA et al, 2013 45 Olsson M.E. et al, 2004 47 Sergazy S et al, 2023 50 Bunea A et al, 2013 51 Black currants Ribes lacustre…”