Body composition and laboratory parameters in children with down syndrome: The DONUT study

Pecoraro, Luca; Ferron, Elena; Solfa, Martina; Mirandola, Massimo; Lauriola, Silvana; Piacentini, Giorgio; Pietrobelli, Angelo

doi:10.1016/j.clnesp.2023.07.003

Cited by 3 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Children with DS are at increased risk of SDB due to features commonly associated with the syndrome, such as a small oropharynx, midface hypoplasia, narrow nasopharynx, and macroglossia. Additionally, factors such as obesity, hypothyroidism, and other medical comorbidities are also known to contribute to the severity of SDB [26,27].…”

Section: Obesity In Down Syndromementioning

confidence: 99%

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

Voltan,

Concer,

Pecoraro

et al. 2024

Preprint

View full text Add to dashboard Cite

Furthermore, the nasal congestion typical of rhinitis can contribute to upper airway obstruction and sleep-disordered breathing. A vicious circle is created between asthma and sleep-disordered breathing: uncontrolled asthma and sleep-disordered breathing can worsen each other. In children with genetic obesity, despite alterations in the immune system, fewer allergies are found compared to the general population. The causes of this reduced allergenicity are unclear but probably involve genetic, immunological, and environmental factors. Further studies are needed to understand the mechanisms. The study emphasizes the importance of jointly evaluating and managing allergies, obesity, and sleep-disordered breathing in children, considering their close interconnection.

show abstract

Section: Obesity In Down Syndromementioning

confidence: 99%

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

Voltan,

Concer,

Pecoraro

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Section: Obesity In Down Syndromementioning

confidence: 99%

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing in Children

Voltan,

Concer,

Pecoraro

et al. 2024

Children

Self Cite

View full text Add to dashboard Cite

This narrative review study investigates the correlations between obesity, allergies, and sleep-disordered breathing in pediatric populations. Searches for pertinent articles were conducted on the Medline PubMed Advanced Search Builder, Scopus, and Web of Science databases from unlimited to April 2024. Sleep-disordered breathing causes repeated upper airway obstructions, leading to apneas and restless sleep. Childhood obesity, which affects around 20% of children, is often associated with sleep-disordered breathing and allergies such as asthma and allergic rhinitis. It is distinguished between diet-induced obesity (resulting from excess of diet and physical inactivity) and genetic obesity (such as is seen in Down syndrome and Prader–Willi syndrome). In children with diet-induced obesity, chronic inflammation linked to weight can worsen allergies and increase the risk and severity of asthma and rhinitis. Furthermore, the nasal congestion typical of rhinitis can contribute to upper respiratory tract obstruction and obstructive sleep apnea. A vicious circle is created between asthma and sleep-disordered breathing: uncontrolled asthma and sleep-disordered breathing can worsen each other. In children with genetic obesity, despite alterations in the immune system, fewer allergies are observed compared to the broader population. The causes of this reduced allergenicity are unclear but probably involve genetic, immunological, and environmental factors. Additional research is necessary to elucidate the underlying mechanisms. The present narrative review study emphasizes the importance of jointly evaluating and managing allergies, obesity, and obstructive sleep apnea in children considering their close interconnection.

show abstract

The effects of resistance training on health-related physical fitness of people with down syndrome – A systematic review and meta-analysis

Stojanović,

Rančić,

Ilić

et al. 2024

Disability and Rehabilitation

View full text Add to dashboard Cite

Body composition and laboratory parameters in children with down syndrome: The DONUT study

Cited by 3 publications

References 28 publications

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing in Children

The effects of resistance training on health-related physical fitness of people with down syndrome – A systematic review and meta-analysis

Contact Info

Product

Resources

About