Bolus or infusion teicoplanin for intravascular catheter associated infections in immunocompromised patients?

Ley, B. E.; Jalil, Nur Asyilla Che; McIntosh, Jamie; Smart, A.; Wilson, Michael; Foot, A. B. M.; Millar, Michael

doi:10.1093/jac/38.6.1091

Cited by 16 publications

(6 citation statements)

References 9 publications

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“…Table 3 summarizes current recommendations based upon consensus and the literature, although the decision to salvage or remove a catheter should be made following discussion with the microbiologist and after consideration of the patient's clinical status and his position on the treatment pathway. Recent evidence suggests that in situ use of glycopeptides may be effective for coagulase negative staphylococcal infections (Ley et al. , 1996; Giacometti et al.…”

Section: Major Recommendationsmentioning

confidence: 99%

Guidelines on the insertion and management of central venous access devices in adults

Bishop

Dougherty

Bodenham

et al. 2007

Int J Lab Hematology

236

189

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Central venous access devices are used in many branched of medicine where venous access is required for either long-term or a short-term care. These guidelines review the types of access devices available and make a number of major recommendations. Their respective advantages and disadvantages in various clinical settings are outlined. Patient care prior to, and immediately following insertion is discussed in the context of possible complications and how these are best avoided. There is a section addressing long-term care of in-dwelling devices. Techniques of insertion and removal are reviewed and management of the problems which are most likely to occur following insertion including infection, misplacement and thrombosis are discussed. Care of patients with coagulopathies is addressed and there is a section addressing catheter-related problems.

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Section: Major Recommendationsmentioning

confidence: 99%

Guidelines on the insertion and management of central venous access devices in adults

Bishop

Dougherty

Bodenham

et al. 2007

Int J Lab Hematology

236

189

View full text Add to dashboard Cite

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“…This allows outpatient treatment for afebrile clinically stable patients. Considering the pharmacokinetic-pharmacodynamic relationships described above, it seems reasonable to extend the period of administration to several hours [144]. As an adjunct, antibiotic lock therapy can be added to the short infusion.…”

Section: G L Y C O P E P T I D E Smentioning

confidence: 99%

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Simon

Bode

Beutel

2006

Clinical Microbiology and Infection

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Otherwise unexplained clinical signs of infection in patients with long-term tunnelled or totally implanted central venous access devices (CVADs) are suspected to be CVAD-associated. Diagnostic methods include catheter swabs, blood cultures and cultures of the catheter tip or port reservoir. In the case of a suspected CVAD-related bloodstream infection in paediatric oncology patients, in-situ treatment without prompt removal of the device can be attempted. Removal of the CVAD should be considered if bacteraemia persists or relapses > or = 72 h after the initiation of (in-vitro effective) antibacterial therapy administered through the line. Timely removal of the device is also recommended if the patient suffers from a complicated infection, or if Staphylococcus aureus, Pseudomonas aeruginosa, multiresistant Acinetobacter baumannii or Candida spp. are isolated from blood cultures. Duration of therapy depends on the immunological recovery of the patient, the pathogen isolated and the presence of related complications, such as thrombosis, pneumonia, endocarditis and osteomyelitis. Antibiotic lock techniques in addition to systemic treatment are beneficial for Gram-positive infections. Although prospectively controlled studies are lacking, the concomitant use of urokinase locks and taurolidine secondary prophylaxis seem to favour catheter salvage.

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“…The rationale, to increase the duration of exposure of organisms colonising the CVC to antibiotics, is based on evidence that bactericidal action is time dependent. 39 We did not conduct a systematic review of this option for two reasons. First, we found no relevant studies for slow infusion compared with bolus administration of antibiotics (see Figure 5).…”

Section: Antimicrobial Locks To Prevent Cvc-associated Infectionmentioning

confidence: 99%

Accuracy of bacterial DNA testing for central venous catheter-associated bloodstream infection in children with cancer

Millar

Zhou²,

Skinner³

et al. 2011

Health Technol Assess

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Bolus or infusion teicoplanin for intravascular catheter associated infections in immunocompromised patients?

Cited by 16 publications

References 9 publications

Guidelines on the insertion and management of central venous access devices in adults

Guidelines on the insertion and management of central venous access devices in adults

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Accuracy of bacterial DNA testing for central venous catheter-associated bloodstream infection in children with cancer

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