Bone Formation Induced by Epithelium Of Urinary Bladder

Anspach, William E.

doi:10.1001/archsurg.1964.01320030036006

Cited by 8 publications

(1 citation statement)

References 27 publications

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“…15 There have been numerous studies demonstrating the ability of transplanted urinary bladder epithelium to induce bone formation in soft tissues. [15][16][17] This phenomenon has been studied and produces consistent results in dogs, cats, rabbits, gerbils and guinea pigs. 16 17 Histopathology in this patient demonstrated foci of immature woven bone lined by a single layer of plump well-differentiated osteoblasts.…”

Section: Discussionmentioning

confidence: 71%

Imaging and histopathological characteristics of carcinoma‐induced bone formation in skeletal muscle

Luce

Magagna

Smith

et al. 2019

Vet Record Case Reports

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An 11-year-old neutered male Groenendael canine presented with suspected neoplastic disease associated with pelvic limb lameness. Clinical examination revealed firm and thickened ventral abdominal musculature, pitting oedema with a spiculated texture within pelvic limb and inguinal subcutaneous tissues, sublumbar lymphadenopathy and multifocal hard foci along the floor of the pelvic canal. CT revealed a severe active polyostotic periosteal reaction and muscular mineralisation of the hindlimbs and caudal trunk. Skeletal muscle biopsy revealed a histopathological diagnosis of metastatic carcinoma with chondroid osseous metaplasia characterised by ossification (bone formation) within the tissue matrix. Paliative therapy was provided for the dog for two weeks before being euthanized.

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Section: Discussionmentioning

confidence: 71%

Imaging and histopathological characteristics of carcinoma‐induced bone formation in skeletal muscle

Luce

Magagna

Smith

et al. 2019

Vet Record Case Reports

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Heterotopic ossification in the pulmonary metastases of gastric adenocarcinoma.Report of a case and review of the literature

Rhone

Horowitz

1976

Cancer

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A case of heterotopic ossification in the pulmonary metastases of an adenocarcinoma of the stomach is presented. This report represents the second known case in the world literature. Three cases with ossification in the primary tumor of the stomach and three cases of colorectal adenocarcinoma with ossification in the pulmonary metastases have been reported. The findings in these reports are reviewed and compared with those in the present case. The observations in these cases are consistent with the theory that heterotopic ossification in tumors and/or their metastases is due to metaplasia of fibroblasts induced by the presence of malignant cells.

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Experimental Production of Ectopic Bone

Connor

1983

Soft Tissue Ossification

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Bone Formation Induced by Epithelium Of Urinary Bladder

Cited by 8 publications

References 27 publications

Imaging and histopathological characteristics of carcinoma‐induced bone formation in skeletal muscle

Imaging and histopathological characteristics of carcinoma‐induced bone formation in skeletal muscle

Heterotopic ossification in the pulmonary metastases of gastric adenocarcinoma.Report of a case and review of the literature

Experimental Production of Ectopic Bone

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