Bone mineral density and association of osteoarthritis with fracture risk

Chan, Mei Yen; Eisman, John A.; Nguyen, Tuan V.

doi:10.1016/j.joca.2014.07.004

Cited by 40 publications

(25 citation statements)

References 39 publications

(35 reference statements)

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“…Fall history and knee OA (vs. neither or only one) was associated with worse KOOS-QoL and SF12 Physical Component Summary scores, in persons with or at higher risk for knee OA in the Osteoarthritis Initiative (19). Fracture risk was higher in women with OA (Dubbo Osteoporosis Epidemiology Study) than those without OA; however, the association was mainly observed in women with osteopenic BMD (for vertebral and limb fracture, but not hip fracture) and normal BMD and not in those with osteoporosis (20). …”

Section: Resultsmentioning

confidence: 98%

Osteoarthritis year in review 2015: clinical

Sharma

2016

Osteoarthritis and Cartilage

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The purpose of this review is to highlight clinical research in osteoarthritis. A literature search was conducted using PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) with the search terms “osteoarthritis [All Fields] AND treatment [All Fields]” and the following limits activated: humans, English language, all adult 19+ years, published between April 1, 2014 and April 1, 2015. A second literature search was then conducted with the search terms “osteoarthritis [All Fields] AND epidemiology [All Fields]”, with the same limits. Reports of surgical outcome, case series, surgical technique, tissue sample or culture studies, trial protocols, and pilot studies were excluded. Of 1523, 148 were considered relevant. Among epidemiologic and observational clinical studies, themes included physical activity, early knee OA, and confidence/instability/falls. Symptom outcomes of pharmacologic treatments were reported for methotrexate, adalimumab, anti-nerve growth factor monoclonal antibodies, strontium ranelate, bisphosphonates, glucosamine, and chondroitin sulfate, and structural outcomes of pharmacologic treatments for strontium ranelate, recombinant human fibroblast growth factor 18, and glucosamine and chondroitin sulfate. Symptom outcomes of non-pharmacologic interventions were reported for: neuromuscular exercise, quadriceps strengthening, weight reduction and maintenance, TENS, therapeutic ultrasound, stepped care strategies, cognitive behavior therapy for sleep disturbance, acupuncture, gait modification, booster physical therapy, a web-based therapeutic exercise resource center for knee OA; hip physical therapy for hip OA; and joint protection and hand exercises for hand OA. Structure outcomes of non-pharmacologic interventions were reported for patellofemoral bracing.

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Section: Resultsmentioning

confidence: 98%

Osteoarthritis year in review 2015: clinical

Sharma

2016

Osteoarthritis and Cartilage

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“…This would explain the occurrence of a dislocation instead of a femoral neck fracture and, also, the occurrence of a pure dislocation, i.e., not accompanied by any fracture of the acetabulum. However, the clinical correlation between hip osteoarthritis and fracture of the proximal femur remains controversial [16][17][18][19]. Finally, some suggested that a low anteversion of the proximal femur or even a retroversion would favor a traumatic hip dislocation [3,20].…”

Section: Discussionmentioning

confidence: 99%

Are traumatic hip dislocations of the young and the elderly comparable: review of the literature from a recent case

Gerosa

Aurégan

Letellier

et al. 2015

Eur Orthop Traumatol

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Traumatic hip dislocation is a condition mostly encountered among young patients. However, clinical series reported regularly cases among elderly. From those, it seems that traumatic hip dislocation in young and elderly patients have a different profile. We present the case of a traumatic hip dislocation in a patient of 81 years secondary to a fall from his height. No fracture occurred. The dislocation was reduced by external maneuvers 3 h after the trauma. At last follow-up of 1 year, the patient developed a secondary hip osteoarthritis despite any articular incongruence. From a review of the literature, we found that epidemiology, pathophysiology, and prognosis of traumatic dislocation of the hip in the elderly may be different than those in young subjects. Hence, we suggest that the two conditions should be separated.Level of evidence: V. Expert opinion.

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“…The role of the combination of osteoarthritis and osteoporosis in the occurrence of fractures has been reported in the prospective dubbo osteoporosis epidemiology study [40]. As compared with individuals without osteoarthritis, individuals with self-reported osteoarthritis were older, had higher BMI and BMD (in spine and femoral neck) and more frequently a recent fall.…”

Section: Bmd-bmi Interaction In Osteoarthritismentioning

confidence: 95%

“…Earlier studies [49,50] have indicated that a large proportion of patients awaiting total arthroplasty of the hip or knee because of osteoarthritis also have osteoporosis. An interesting finding of the Australian study [40] is that one out of five women and men with osteoporosis had self-reported osteoarthritis. In these patients with osteoporosis, fracture risk was similar between patients with and without osteoarthritis.…”

Section: Do Osteoporosis and Osteoarthritis Coexist?mentioning

confidence: 99%