Bone mineral density in healthy Syrian women measured by dual energyX-ray absorptiometry

Abstract

Assessment of bone mineral density (BMD) using dual energy X-ray absorptiometry (DXA) technique is considered as a standard technique for diagnosing osteopenia and osteoporosis and evaluating the severity of such diseases. Numerous studies have demonstrated the necessity to establish an ethnicspecific reference data for Bone mineral density measurements. Such data are lacking for the Syrian population. The objectives of this study are (1) to establish BMD reference values in a group of healthy Syrian women using DXA technique, (2) to compare with values from other populations, (3) to study the prevalence of osteopenia and osteoporosis in Syrian women using the manufacturer reference values. A total of 951 healthy Syrian women aged 20-79 years participated in this study. Weight, height, and BMI have been determined. BMD measurements were performed using Lunar Prodigy Advance System (GE). The data were compared with those from other populations. The results have demonstrated the expected decline in BMD with age after peaking at 30-39 years old group. The peak values of the lumbar spine and femur neck were 1.16 (0.12), and 0.95 (0.13) g/cm 2 , respectively. The results of the Syrian women were compared with those from other populations and the differences were presented. Osteopenia was diagnosed in 35.80% and 60.31% and osteoporosis in 6.23% and 2.72% in lumbar spine and femur neck, respectively, of women 50-59 years of age. These ratios increased to 36.84%, 68.42% and 23.68%, 13.10%, respectively, in the age group more than 59 years. BMD values of the Syrian women were determined for the first time. The results demonstrate the importance of establishing population-specific reference range for BMD values for an accurate assessment of Osteoporosis. High prevalence of osteopenia and osteoporosis was demonstrated in Syrian using the manufacturer reference values.

Association of Anti-Mullerian Hormone and 25-Hydroxyvitamin D in women with low bone mineral density in Babylon, Iraq

“…In our results, 145 females were examined by DEXA scan, of whom (55.17%) were diagnosed as abnormal bone mineral density and (44.83%) were with normal bone mineral density results. This is in accordance with other studies in Saudi, Syrian and Iranian women, [23][24][25][26]. While this is in discordance with Brazilian study, 36.5% of women had normal BMD, and 63.5% were diagnosed with abnormal BMD [27].…”

Knowledge and Awareness of Osteoporosis and Its Risk Factors Among the Adult Population in Jeddah, Saudi Arabia: An Analytical Cross-Sectional Study

“…Furthermore, the prevalence of this disease in the Middle East is 24.4%, with Saudi Arabia having the highest prevalence and Kuwait having the lowest [ 4 ]. Additionally, as concluded by Mohammed Bakir et al in their study on 951 Syrian women, 23.68% were diagnosed with osteoporosis in the lumbar spine, while 13.1% had evidence of osteoporosis in the neck of the femur [ 5 ].…”

Assessing the Knowledge and Attitude towards Osteoporosis among Syrian Women: A Cross-Sectional Study

“…Saudi Arabia has the highest prevalence, with 32.7%, while Kuwait has the lowest with 15.1% [ 1 ]. A study from Syria reported that 36.84% of the studied women, which belonged to the age group between 50 and 59, were diagnosed with osteopenia in the lumbar spine and in the femoral neck in 68.42%, while osteoporosis was diagnosed in the lumbar spine in 23.68% of cases and 13.10% in the femoral neck [ 6 ]. 33.3% of women and 16.6% of men will sustain a hip fracture by their ninth decade [ 1 ].…”