2019
DOI: 10.1097/rlu.0000000000002625
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Bone Pseudometastasis on 18F-FDG PET in Japanese Patients With Esophageal Cancer

Abstract: Purpose of the Report False-positive bone lesions mimicking bone metastases (bone pseudometastasis) on 18F-FDG PET/CT have often been reported in patients with esophageal cancer. We aimed to evaluate the prevalence and features of these lesions in Japanese patients with esophageal cancer. Methods In this retrospective study, we analyzed 83 FDG PET/CT studies for initial staging of esophageal cancer, and extracted patients with 1 or more localized high u… Show more

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Cited by 8 publications
(5 citation statements)
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“…[27] In recent years, studies of PET/CT and WB-DWI have highlighted multiple reasons behind the misdiagnosis of bone disease. FDG uptake is observed in numerous scenarios including in ammation [28] , tuberculosis [29] , severe fatty degeneration of bone marrow [30] and so on. WB-DWI and PET/CT were associated with the same di culties in differentiating MM bone disease from non-lesions.…”
Section: Discussionmentioning
confidence: 99%
“…[27] In recent years, studies of PET/CT and WB-DWI have highlighted multiple reasons behind the misdiagnosis of bone disease. FDG uptake is observed in numerous scenarios including in ammation [28] , tuberculosis [29] , severe fatty degeneration of bone marrow [30] and so on. WB-DWI and PET/CT were associated with the same di culties in differentiating MM bone disease from non-lesions.…”
Section: Discussionmentioning
confidence: 99%
“…[27] In recent years, studies of PET/CT and WB-DWI have highlighted multiple reasons behind the misdiagnosis of bone disease. FDG uptake is observed in numerous scenarios including in ammation [28] , tuberculosis [29] , severe fatty degeneration of bone marrow [30] and so on. WB-DWI and PET/CT were associated with the same di culties in differentiating MM bone disease from non-lesions.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, tumor lymph node metastasis was diagnosed. [1][2][3] Subsequently, the patient was enrolled in the ongoing 68 Ga-FAPI PET/MRI clinical trial (NCT04554719) after signing the informed consent. [4][5][6][7] The abnormal focus with intense FDG uptake was also revealed in the MIP (E, arrow indicated) of 68 Ga-FAPI PET/MRI.…”
Section: Figurementioning
confidence: 99%
“…The axial images of 18 F-FDG PET/CT ( B , PET image; C , CT image; D , PET/CT fused image; arrows indicated) showed an enlarged omental nodule with increased uptake. Therefore, tumor lymph node metastasis was diagnosed 1–3 . Subsequently, the patient was enrolled in the ongoing 68 Ga-FAPI PET/MRI clinical trial (NCT04554719) after signing the informed consent 4–7 .…”
mentioning
confidence: 99%