Bone Quality is Associated with Fragility Fracture in Patients with Hemoglobinopathies
Fung Ellen B,
Sarsour Iman,
Manzo Raquel
et al.
Abstract:Background: Low bone mass is common in adults with thalassemia (Thal) and sickle cell disease (SCD), though disease-specific artifacts may contribute to inaccuracies in bone mineral density (BMD) assessment. Trabecular bone score (TBS), an indicator of bone quality, is not susceptible to these challenges and may improve fracture risk prediction. Methods: A retrospective chart review was conducted in patients with Thal or SCD who had at least one spine BMD scan by DXA performed in the past 10 years. The most re… Show more
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