Bone Remodeling Simulation of Subject-Specific Model of Tibia under Torque

González-Carbonell, Raide A.; Ortiz-Prado, Armando; Cisneros-Hidalgo, Y. A.; Alpizar-Aguirre, A

doi:10.1007/978-3-319-13117-7_79

Cited by 3 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, an understanding of this could be useful for improving the implant design ( Lian et al, 2014 ). Although there are many femoral bone remodeling studies, similar studies on tibial bone are very few ( Perez et al, 2010 ; Robalo, 2011 ; Fang et al, 2013 ; González-Carbonell et al, 2015 ). Moreover, there is no investigation in the literature on bone remodeling in the human tibia considering its piezoelectric properties.…”

Section: Introductionmentioning

confidence: 99%

Computational Analysis of Bone Remodeling in the Proximal Tibia Under Electrical Stimulation Considering the Piezoelectric Properties

Bansod

Kebbach

Kluess

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

The piezoelectricity of bone is known to play a crucial role in bone adaptation and remodeling. The application of an external stimulus such as mechanical strain or electric field has the potential to enhance bone formation and implant osseointegration. Therefore, in the present study, the objective is to investigate bone remodeling under electromechanical stimulation as a step towards establishing therapeutic strategies. For the first time, piezoelectric bone remodeling in the human proximal tibia under electro-mechanical loads was analyzed using the finite element method in an open-source framework. The predicted bone density distributions were qualitatively and quantitatively assessed by comparing with the computed tomography (CT) scan and the bone mineral density (BMD) calculated from the CT, respectively. The effect of model parameters such as uniform initial bone density and reference stimulus on the final density distribution was investigated. Results of the parametric study showed that for different values of initial bone density the model predicted similar but not identical final density distribution. It was also shown that higher reference stimulus value yielded lower average bone density at the final time. The present study demonstrates an increase in bone density as a result of electrical stimulation. Thus, to minimize bone loss, for example, due to physical impairment or osteoporosis, mechanical loads during daily physical activities could be partially replaced by therapeutic electrical stimulation.

show abstract