Bone Sarcoma: Treatment by Irradiation, Amputation, or a Combination of the Two

Longitudinal Growth and Dental Development in Osteosarcoma Patients

“…Our findings do not definitely exclude the possibility that the tumours may have a growth promoting effect as suggested on the basis of hormonal studies in osteosarcoma patients (McMaster et al 1975). However, the time period with symptoms prior to diagnosis was only about 3 months which is in good agreement with that observed in previous reports (Brostrom et al 1980, Sweetnam et al 1971). This period appears to be too short to prove that there is an accelerated growth rate during the pubertal growth spurt.…”

Presenting Symptoms and Treatment Delay in Osteosarcoma and Ewing's Sarcoma

“…The initial symptoms and findings in bone sarcomas are uncharacteristic, and most commonly consist of pain, and in some rare cases swelling (2,3,6,7,12).…”

The Surgical Treatment and Outcome of Pathological Fractures in Localised Osteosarcoma

“…Local treatment of the tumour without chemotherapy results in survival of 20% at five years (McKenna et al 1966;Sweetnam, Knowelden and Seddon 1971), but with effective chemotherapy this improves to 60% (Link et al 1991;Bramwell et al 1992;Winkler et al 1993).…”