Bone Scintigraphy in Children With Cat Scratch Disease

Donoso, G.; Paulsen, Cesar; Riquelme, Paulina; Lobo, Gabriel; Gutiérrez, Daniela; Pérez, Andrés; Jiménez, César Eduardo

doi:10.1097/rlu.0000000000000240

Cited by 4 publications

(1 citation statement)

References 12 publications

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“…19 These organ involvements and even coexisting vertebrae involvement may not be clinically apparent but can contribute to persistent fevers and illness. [20][21][22] Lymph node disease in our cohort tended to be tender, unilateral, and muti-nodal on imaging with a predominant node and significant overlying cutaneous swelling out in keeping with underlying lymphadenopathy. Cervical and submandibular lymph nodes were most commonly involved in our cohort and as reported in a large case series by Moriarty and Margileth, 23 in contrast to the axillary and epitrochlear regions reported in a majority of the 1,200 cases seen by Carithers.…”

Section: Discussionmentioning

confidence: 97%

Clinical Manifestations Associated with Bartonella henselae Infection in a Tropical Region

Tay

Freeman

Baird

2021

The American Journal of Tropical Medicine and Hygiene

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Bartonella henselae is a zoonotic Gram-negative Bacillus associated with self-limited regional lymphadenopathy. In recent decades, an expanding spectrum of clinical manifestations has been described, in part, due to improved diagnostics. However, updated epidemiological data are sparse. We retrospectively reviewed the clinical features of 31 patients with B. henselae infection over 15 years from 2005 to 2019, in the tropical Top End of Australia. Our annual disease incidence of 1.3 cases per 100,000 population is lower than that in the national database surveillances in the United States, but the hospitalization incidence of 0.9 per 100,000 population in our region is higher than those reported in the literature, with an average length of stay of 9 days. Patients were more commonly male, aboriginal, and aged less than 14 years (median age: 7 years), living in a rural setting with presentation during our monsoon season. The disease spectrum included lymph node disease (74%), organ peliosis, endocarditis, cutaneous lesions, parapharyngeal abscess, parotitis, and neurologic and ocular syndromes. Lymph node disease was far commoner in children than the more serious systemic B. henselae infections associated with adults (P = 0.074). Although no deaths were reported, significant morbidities were observed. Two endocarditis cases presented with glomerulonephritis, and hematological and neurological features mimicking vasculitis, and consequently received immunosuppressants. One case was only diagnosed after representation with serial embolic strokes. Given the heterogeneity of disease manifestations with nonspecific symptoms and significant consequences, a timely and accurate diagnosis is needed to avoid unnecessary treatments or interventions.

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