Book Review: Progress in Molecular and Subcellular Biology. Vol. 1. By B. W. Agranoff, J. Davies, F. E. Hahn, M. G. Mandel, N. S. Scott, R. M. Smillie, and C. R. Woese, edited by F. E. Hahn

Abstract

Amsterdam- London-New York 1970. 1st Edit., 506 pp., bound, Dfl. 70.00. "Metastable ions", i.e. ions which decompose on the way from the ion source to the collector, play an important role in the investigation of mass-spectrometric decomposition processes because they yield information on cleaved-off particles. Metastable ions lead to the formation of relatively broad bands in the corresponding mass spectra. However, the low intensity of such bands makes them difficult or impossible to detect.To facilitate the task of detecting metastable ions Beynon, one of the authors, has evolved an elegant method: normal ions from the ion source of a double-focusing apparatus pass through the field-free space with a kinetic energy E into the electrostatic sector field. In contrast, metastable ions, which are decomposed in the field-free space, carry only the fraction F = Em2/ml of the kinetic energy of the parent ions, ml being the mass of the parent ions and m2 that of the daughter ions. These ions can only pass through the retarding potential if the voltage V in the electrostatic sector field is reduced to the value Vm2/ml. If the voltage is continuously changed from 0 to V, one obtains a spectrum of the kinetic energies of all metastable transition processes. Since in this case there is no overlap with the normal spectrum, this technique constitutes a very sensitive method for investigating metastable ions. With the aid of the present tables the corresponding metastable transition processes can easily be determined from the kinetic energy values, which can be read off directly. This book will therefore be an indispensable and time-saving tool for all laboratories in which IKE (ion kinetic energy) spectra are used for the study of metastable ions.Spiteffer [NB 923 IE] Disinfection. Edited by M. A. Bernarde. Marcel Dekker, Inc.This book demonstrates that disinfection still belongs to an underdeveloped area of research. In many cases ultraconservatism -"disinfection rituals" -stands in the way of the few new possibilities in the field of disinfection. In practice, disinfection IS primarily a question of money and of suitable staff. The book is aimed at all people working in research, hygiene, and the foodstuffs industry who are interested in new discoveries in the field of disinfection. Nineteen authors have contributed to the book, most of them giving detailed reports on specialized fields. The collaboration of the team of authors, however laudable in itself, sometimes leads to overlapping and unnecessary repetition.One is inclined to divide the book into a theoretical and a practical and technical part. The first part would have been improved by condensing some parts and expanding others. Bacterial metabolism and mechanisms of action should perhaps have been put in one chapter and the sites of action of the common disinfectants and (in somewhat more detail) those of some antibiotics could have been included in the metabolism and biosynthesis schemes. A few basic theoretical aspects could also have been transferred from ...

Synthesis and coordination chemistry of 4‐azabenzimidazole derivatives

“…3. The Au C carbene bond length (1.977(2)Å) in 20 is nearly identical to the Au-C separations in related gold(I) carbene complexes bearing the benzimidazolin-2-ylidene ligand [33,34]. The Au-Cl bond length (2.2814(6)Å) also falls in the range previously reported for complexes of the type [AuCl(NHC)].…”

“…confirmed by NMR spectroscopy. The resonance for the carbene carbon atom in 20 was observed at δ = 181.5 ppm in the 13 C{ 1 H} NMR spectrum, which is a value typical for complexes of the type [AuX(NHC)] (X = Cl, Br) bearing a benzimidazolin-2-ylidene ligand (δ = 175.8-181.2 ppm) [33]. The N-protecting group is still present and can be detected by the resonance for the carbonyl carbon atom at δ = 198.7 ppm in the 13 C{ 1 H} NMR spectrum.…”

Triply cyclometalated trinuclear iridium(iii) and trinuclear palladium(ii) complexes with a tri-mesoionic carbene ligand

“…11 Even though polynuclear metal complexes have become popular in recent years owing to their augmented catalytic activity 12 compared to 30 their mononuclear counterparts, examples of such complexes with higher nuclearity containing MIC donors remain rare. 13 Recently, we showed that a di-substituted phenylene bridged bistriazolium salt after deprotonation reacts to yield a dinuclear Ir III complex with additional cyclometalation of the central phenyl 35 ring (Fig. 1).…”

“…Upon complexation the resonance for α-hydrogen atoms of the pyridine ring (δ = 8.99 ppm) appeared more downfield shifted compared to their corresponding resonance in free pyridine (δ = 8.62). The 35 characteristic resonance for the Ctrz-Pd carbon atoms was observed at δ = 133.1 ppm in the 13 C{ 1 H} NMR spectrum of complex [4]. This resonance is slightly downfield shifted from the C5H resonance of the precursor triazolium salt 2 (δ = 129.2 ppm).…”

Iridium, ruthenium, and palladium complexes containing a mesoionic fused imidazolylidene ligand

“…The most common ring fusion is of course the annulation of a benzene ring to the C4-C5 bond of the NHC (A, Fig. 1), and indeed a plethora of applications have been disclosed based on the benzimidazole ring structure [23][24][25]. Fused systems that involve one of the imidazole nitrogen atoms (B, C, Fig.…”