Boron thin films and CR-39 detectors in BNCT: A method to measure the 10B(n,α)7Li reaction rate

Smilgys, Bárbara; Guedes, S.; Morales, M.; Alvarez, F.; Hadler, J.C.; Coelho, Paulo; Siqueira, Paulo T.D.; Alencar, I.; Soares, Carlos José; Curvo, Eduardo Augusto Campos

doi:10.1016/j.radmeas.2012.07.001

Cited by 23 publications

(7 citation statements)

References 8 publications

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“…In this work, the samples were irradiated for 1 h, which means a total production of 9.2 × 10 −9 alpha particles from the initial amount of the 10 B target atoms. This result is in agreement with a previous work in which the activation of thin films of boron was studied [ 31 ].…”

Section: Resultssupporting

confidence: 93%

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy

et al. 2017

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Currently, nanostructured compounds have been standing out for their optical, mechanical, and chemical features and for the possibilities of manipulation and regulation of complex biological processes. One of these compounds is boron nitride nanotubes (BNNTs), which are a nanostructured material analog to carbon nanotubes, but formed of nitrogen and boron atoms. BNNTs present high thermal stability along with high chemical inertia. Among biological applications, its biocompatibility, cellular uptake, and functionalization potential can be highlighted, in addition to its eased utilization due to its nanometric size and tumor cell internalization. When it comes to new forms of therapy, we can draw attention to boron neutron capture therapy (BNCT), an experimental radiotherapy characterized by a boron-10 isotope carrier inside the target and a thermal neutron beam focused on it. The activation of the boron-10 atom by a neutron generates a lithium atom, a gamma ray, and an alpha particle, which can be used to destroy tumor tissues. The aim of this work was to use BNNTs as a boron-10 carrier for BNCT and to demonstrate its potential. The nanomaterial was characterized through XRD, FTIR, and SEM. The WST-8 assay was performed to confirm the cell viability of BNNTs. The cells treated with BNNTs were irradiated with the neutron beam of a Triga reactor, and the apoptosis caused by the activation of the BNNTs was measured with a calcein AM/propidium iodide test. The results demonstrate that this nanomaterial is a promising candidate for cancer therapy through BNCT.

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Section: Resultssupporting

confidence: 93%

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy

et al. 2017

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“…The most important features of CR-39 are its sensitivity, stability and the uniformity also it has an important feature that it can alter its response within limits by suitable choice of etching condition. CR-39 is used extensively to give data in a different field such as Brachytherapy [5], Boron Neutron Capture Therapy BNCT [6][7], U-exploration Galleries [8][9], and measurements of Radon in building materials [10].…”

Section: Cr-39mentioning

confidence: 99%

“…Also, Najeba et al, [16] measured V B as 1.174 μm/h, and Matiullah et al, [17] measured V B as 1.25 μm/h. Figure (6) shows the track etch rate determined from Equation (3) for different etching times ranging from 4 to 8 hours. The Figure shows that the track etch rate increases with time, peaking at around 5 hours etching time before declining.…”

Section: The Track Parameters For Naoh Etchantmentioning

confidence: 99%

Evaluation of CR-39 Track Parameters by Utilizing Chemical Organic Additives to NaOH Etchant

2021

Journal of Measurement Science and Applications (JMSA)

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The nuclear track detector, CR-39, is widely used for detecting Alpha-particles which produce latent tracks on it and can be enlarged by using a suitable chemical etchant to be visible under an optical microscope. The commonly used etchant is an aqueous 6.25 N solution of NaOH at 70° C. The behavior of the track parameters were studied at different etching times using direct measurements of the track opening diameters. These parameters were re-evaluated after adding some organic solution to the Sodium Hydroxide etchant to improve the etching conditions and so the quality of the tracks. These parameters including the track density, track diameter, the bulk, and the track etch rates, as well as track length, and depth. It has been found that Methanol and Ethanol additives led to a decrease of the bulk and track etch rates but with about 30% increasing of the track etch rate ratio compared with their values in case of using NaOH without any additives. In the case of using Benzene and Acetone additives, there is no remarkable changes in these parameters. On the other hand, the etching efficiency was increasing more than the double in case of Methanol and Ethanol and decreasing near the half in case of benzene and acetone.

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“…Solid state nuclear track detectors (SSNTD) are materials such as inorganic crystals, plastics, and glasses, known to record the path of charged particles. There are several applications for SSNTD in nuclear science; for instance, measurements of radon gas (Brown, Solomon, & Tinker, ), boron neutron capture therapy (Smilgys et al, ), and age determination by fission track dating (Goto & Danhara, ; Imayama et al, ; Ninomiya et al, ; Takagi, Tsutsui, Arai, Iwano, & Danhara, ; Wagner & Van den Haute, ; Yuguchi et al, ).…”

Section: Introductionmentioning

confidence: 99%

Segmentation of nearly isotropic overlapped tracks in photomicrographs using successive erosions as watershed markers

Siqueira

Nakasuga

Guedes

et al. 2019

Microscopy Res & Technique

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Introduction Procedures for measuring and counting tracks are time‐consuming and involve practical problems. The precision of automatic counting methods is not satisfactory yet; the major challenges are distinguishing tracks and material defects, identifying small tracks and defects of similar size, and detecting overlapping tracks. Materials and Methods Here, we address the overlapping tracks issue using the algorithm Watershed Using Successive Erosions as Markers (WUSEM), which combines the watershed transform, morphological erosions and labeling to separate regions in photomicrographs. We tested this method in two data sets of diallyl phthalate (DAP) photomicrographs and compared the results when counting manually and using the classic watershed and H‐watershed transforms. Results The mean automatic/manual efficiency counting ratio when using WUSEM in the test data sets is 0.97 ± 0.11. Conclusion WUSEM shows reliable results when used in photomicrographs presenting almost isotropic objects. Also, diameter and eccentricity criteria may be used to increase the reliability of this method.

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Boron thin films and CR-39 detectors in BNCT: A method to measure the 10B(n,α)7Li reaction rate

Cited by 23 publications

References 8 publications

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy

Evaluation of CR-39 Track Parameters by Utilizing Chemical Organic Additives to NaOH Etchant

Segmentation of nearly isotropic overlapped tracks in photomicrographs using successive erosions as watershed markers

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